合成RNA与喹吖因及其类似物相互作用的光谱研究。
Spectroscopic studies of the interaction of synthetic RNAs with quinacrine and its analogs.
作者信息
Nakamura S, Yoshimatsu S, Murakami K, Kubota Y
机构信息
Department of Chemistry, Faculty of Science, Yamaguchi University, Japan.
出版信息
Nucleic Acids Symp Ser. 1992(27):75-6.
PMID:1283918
Abstract
The interaction of synthetic RNAs with quinacrine (QAC) and its analogs has been studied by absorption, fluorescence and circular dichroism (CD) measurements. The results indicate that the 2-methoxy group of the acridine ring plays an important role in the appearance of the new absorption band upon binding of QAC to poly-(rA).poly(rU).
摘要
通过吸收光谱、荧光光谱和圆二色光谱（CD）测量研究了合成RNA与喹吖因（QAC）及其类似物的相互作用。结果表明，吖啶环上的2-甲氧基在QAC与聚（rA）·聚（rU）结合时新吸收带的出现中起重要作用。
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