与合成双链多聚核糖核苷酸复合的奎纳克林对映体的荧光特性。
Fluorescence properties of quinacrine enantiomers complexed with synthetic double-stranded polyribonucleotides.
作者信息
Tani S, Kubota Y
机构信息
Department of Chemistry, Faculty of Science, Yamaguchi University, Japan.
出版信息
Nucleic Acids Symp Ser. 1997(37):101-2.
The interaction of quinacrine (QAC) enantiomers with poly(A).poly(U) and poly(I).poly(C) has been studied by fluorescence spectroscopy. The fluorescence and fluorescence-excitation spectra of QAC enantiomers complexed with the polyribonucleotides showed a marked dependence on the excitation and emission wavelengths. This behavior of the bound QAC enantiomers was almost independent of the chirality of the cationic side chain and was very similar to that of the bound racemic QAC.
通过荧光光谱法研究了奎纳克林（QAC）对映体与聚（A）·聚（U）和聚（I）·聚（C）的相互作用。与多聚核糖核苷酸复合的QAC对映体的荧光和荧光激发光谱显示出对激发和发射波长的显著依赖性。结合的QAC对映体的这种行为几乎与阳离子侧链的手性无关，并且与结合的外消旋QAC的行为非常相似。
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