Vanderijst J F, Vandeleene B, De Plaen J F, Kolanowski J
Département de Médecine Interne, Cliniques Universitaires St Luc, (U.C.L.), Bruxelles, Belgique.
Acta Clin Belg. 1992;47(6):408-13. doi: 10.1080/17843286.1992.11718263.
The presence of hypokalaemia in hypertensive patient must prompt a search for increased mineralocorticoid activity. We describe and discuss the observation of a patient with biological markers of hypermineralocorticoidism, despite low plasma and urinary aldosterone levels, and suppressed plasma renin activity. This typical syndrome of apparent mineralocorticoid excess was secondary, in our patient, to prolonged administration of a mineralocorticoid-containing nasal spray.
高血压患者出现低钾血症时,必须查找是否存在盐皮质激素活性增加的情况。我们描述并讨论了一名患者的观察结果,该患者虽血浆和尿醛固酮水平较低且血浆肾素活性受抑制,但具有盐皮质激素过多的生物学标志物。在我们的患者中,这种典型的表观盐皮质激素过多综合征继发于长期使用含盐皮质激素的鼻喷雾剂。