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[博来霉素乳剂用于晚期口咽癌的瘤内注射。局部应用博来霉素的病例报告]

[Bleomycin emulsion for intralesional instillation in advanced oropharyngeal carcinomas. A case report on local bleomycin application].

作者信息

Merten H A, Hönig J F

机构信息

Kieferchirurgische Abteilung, Universitätsklinik Göttingen.

出版信息

Dtsch Zahn Mund Kieferheilkd Zentralbl. 1992;80(5):287-90.

PMID:1284033
Abstract

Local therapy of head and neck cancer using a special bleomycin emulsion as an intratumoral applicarted cytotoxic agent is not established in regular antitumor therapy. It's use only is supposed to be regarded as an "ultima ratio" possibility when other usual methods like surgery, radiotherapy or systemic cytostatic therapy have failed. The procedure of intralesional bleomycin emulsion application will be described and the advantages and disadvantages will be discussed by means of a long-term case report.

摘要

在常规抗肿瘤治疗中,尚未确立使用一种特殊的博来霉素乳剂作为瘤内应用的细胞毒性药物对头颈部癌症进行局部治疗的方法。只有在手术、放疗或全身细胞抑制疗法等其他常用方法均告失败时,才可将其使用视为一种“万不得已”的可能性。本文将描述瘤内注射博来霉素乳剂的操作过程,并通过一份长期病例报告探讨其优缺点。

相似文献

1
[Bleomycin emulsion for intralesional instillation in advanced oropharyngeal carcinomas. A case report on local bleomycin application].[博来霉素乳剂用于晚期口咽癌的瘤内注射。局部应用博来霉素的病例报告]
Dtsch Zahn Mund Kieferheilkd Zentralbl. 1992;80(5):287-90.
2
[Cytostatic primary therapy of squamous cell carcinoma of the oro- and hypopharynx with cisplatin, bleomycin and methotrexate].[顺铂、博来霉素和甲氨蝶呤对头颈部鳞状细胞癌的细胞毒性初始治疗]
Laryngol Rhinol Otol (Stuttg). 1986 Jan;65(1):7-10.
3
The role of intratumour therapy with electroporation and bleomycin in the management of advanced squamous cell carcinoma of the head and neck.电穿孔联合博来霉素瘤内治疗在晚期头颈部鳞状细胞癌管理中的作用
Eur J Surg Oncol. 2005 Nov;31(9):1029-35. doi: 10.1016/j.ejso.2005.04.007. Epub 2005 Sep 8.
4
[Local intratumor chemotherapy. Its indications, performance and risks].[局部肿瘤内化疗。其适应证、操作及风险]
Schweiz Monatsschr Zahnmed. 1995;105(1):71-9.
5
Pretreatment with chemotherapy in patients with advanced head and neck cancer.晚期头颈癌患者的化疗预处理。
J Otolaryngol. 1985 Dec;14(6):391-3.
6
[Pathohistologic studies of serial sections of squamous cell cancer of the oral cavity and oropharynx following cytostatic induction therapy with bleomycin and cisplatin].[口腔和口咽鳞状细胞癌经博来霉素和顺铂细胞抑制诱导治疗后的连续切片病理组织学研究]
Laryngol Rhinol Otol (Stuttg). 1988 Nov;67(11):580-5.
7
Comparison of intratumoral administration of cisplatin versus bleomycin for treatment of periocular squamous cell carcinomas in horses.顺铂与博来霉素瘤内注射治疗马眼周鳞状细胞癌的比较。
Am J Vet Res. 1997 Apr;58(4):431-6.
8
[Effect of chemotherapy on the survival of patients with far-advanced squamous cell carcinoma of the head and neck. A comparative matched-pair analysis of conventional therapeutic procedures with and without chemotherapy].
Laryngol Rhinol Otol (Stuttg). 1986 Jan;65(1):11-5.
9
[Bleomycin in the intratumoral treatment of advanced squamous cell carcinomas in the oto-rhino-laryngological region (author's transl)].
Laryngol Rhinol Otol (Stuttg). 1977 Jun;56(6):543-5.
10
Neoadjuvant chemotherapy in early-stage and locally advanced small bulk squamous cell carcinoma of the oral cavity and oropharynx.口腔及口咽早期和局部晚期小体积鳞状细胞癌的新辅助化疗
Isr J Med Sci. 1988 Sep-Oct;24(9-10):539-44.

引用本文的文献

1
Advanced and rapidly progressing head and neck cancer: good palliation following intralesional bleomycin.晚期进展迅速的头颈癌:瘤内注射博来霉素后缓解良好。
BMJ Case Rep. 2011 Sep 19;2011:bcr0820114599. doi: 10.1136/bcr.08.2011.4599.