Xu Ming, De Giacomo Fabio, Paterson Duncan E, George Tesmol G, Vasella Andrea
Laboratorium für Organische Chemie, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
Chem Commun (Camb). 2003 Jun 21(12):1452-3.
The preparation of 8-substituted guanines using a new phosphorus(III)-mediated cyclisation of 4-acylamino-5-nitrosopyrimidines as the key step is described.
描述了以4-酰氨基-5-亚硝基嘧啶的新型磷(III)介导的环化反应为关键步骤制备8-取代鸟嘌呤的方法。