一种制备8-取代鸟嘌呤的改进方法。
An improved procedure for the preparation of 8-substituted guanines.
作者信息
Xu Ming, De Giacomo Fabio, Paterson Duncan E, George Tesmol G, Vasella Andrea
机构信息
Laboratorium für Organische Chemie, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
出版信息
Chem Commun (Camb). 2003 Jun 21(12):1452-3.
PMID:12841287
Abstract
The preparation of 8-substituted guanines using a new phosphorus(III)-mediated cyclisation of 4-acylamino-5-nitrosopyrimidines as the key step is described.
摘要
描述了以4-酰氨基-5-亚硝基嘧啶的新型磷（III）介导的环化反应为关键步骤制备8-取代鸟嘌呤的方法。
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