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腹壁疝:感染风险因素与资源利用

Abdominal wall hernias: risk factors for infection and resource utilization.

作者信息

Dunne James R, Malone Debra L, Tracy J Kathleen, Napolitano Lena M

机构信息

Department of Surgery, Veterans Affairs Maryland Health Care System, Baltimore, Maryland, USA.

出版信息

J Surg Res. 2003 May 1;111(1):78-84. doi: 10.1016/s0022-4804(03)00077-5.

Abstract

BACKGROUND

Abdominal wall hernia repairs are common surgical procedures. Several recent reports have studied the outcomes of elderly patients undergoing inguinal hernia repair and documented a morbidity rate ranging from 5-57% and a mortality rate ranging from 1.6-14%. However, there has been limited data documenting the risk factors associated with postoperative morbidity and mortality from abdominal wall hernia repairs in general. Therefore, we sought to investigate the incidence of complications in patients undergoing abdominal wall hernia repair and to evaluate the risk factors for infection and resource utilization in these patients.

METHODS

Prospective data (NSQIP) were collected on 6301 noncardiac surgical patients at the VA Maryland Healthcare System from 1995 to 2000. From this data set, 487 (7.7%) patients underwent abdominal wall hernia repairs and comprised the study cohort. Logistic and linear regression analyses were performed to identify risk factors for infection and hospital length of stay.

RESULTS

The mean age of the study cohort was 60 +/- 14 and the mean ASA class was 2.4 +/- 0.7. Descriptive data revealed 99% were male, 43% used tobacco, 8.4% were diabetic, 7.4% used alcohol, 6.3% had chronic obstructive pulmonary disease (COPD), 2.1% were malnourished (defined as >/= 10% weight loss over prior 6 months), 1.6% used steroids, 1.2% had ascites, and 0.2% had coronary artery disease (CAD). The mortality rate was low at 1% but the morbidity rate was higher with a 4.3% incidence of wound infections and a 15.1% incidence of recurrent hernias. The mean preoperative serum albumin level was 4.1 +/- 0.6 g/dL, and the mean hospital length of stay was 1.4 +/- 4.8 days. Multiple logistic and linear regression analyses documented that CAD, COPD, low preoperative serum albumin, and steroid use were independent risk factors for increased postoperative wound infections (P < 0.05) and increased hospital length of stay (P < 0.05).

CONCLUSIONS

Abdominal wall hernia repair is associated with significant morbidity in this predominantly elderly cohort but mortality rates were low. COPD and low preoperative serum albumin were independent predictors of wound infections and CAD, COPD, low preoperative serum albumin, and steroid use were independent predictors of increased hospital length of stay. Therefore, consideration should be given to optimizing patient's cardiopulmonary and nutritional status before abdominal wall hernia repair.

摘要

背景

腹壁疝修补术是常见的外科手术。最近的几份报告研究了老年患者腹股沟疝修补术的结果,记录的发病率为5%-57%,死亡率为1.6%-14%。然而,总体而言,记录腹壁疝修补术后发病和死亡相关危险因素的数据有限。因此,我们试图调查接受腹壁疝修补术患者的并发症发生率,并评估这些患者感染和资源利用的危险因素。

方法

收集了1995年至2000年在马里兰州退伍军人医疗保健系统接受非心脏手术的6301例患者的前瞻性数据(国家外科质量改进计划)。从该数据集中,487例(7.7%)患者接受了腹壁疝修补术,构成了研究队列。进行逻辑回归和线性回归分析以确定感染和住院时间的危险因素。

结果

研究队列的平均年龄为60±14岁,平均美国麻醉医师协会(ASA)分级为2.4±0.7。描述性数据显示,99%为男性,43%吸烟,8.4%患有糖尿病,7.4%饮酒,6.3%患有慢性阻塞性肺疾病(COPD),2.1%营养不良(定义为在过去6个月内体重减轻≥10%),1.6%使用类固醇,1.2%有腹水,0.2%有冠状动脉疾病(CAD)。死亡率较低,为1%,但发病率较高,伤口感染发生率为4.3%,复发性疝发生率为15.1%。术前血清白蛋白平均水平为4.1±0.6g/dL,平均住院时间为1.4±4.8天。多项逻辑回归和线性回归分析表明,CAD、COPD、术前血清白蛋白水平低和使用类固醇是术后伤口感染增加(P<0.05)和住院时间延长(P<0.05)的独立危险因素。

结论

在这个以老年患者为主的队列中,腹壁疝修补术与显著的发病率相关,但死亡率较低。COPD和术前血清白蛋白水平低是伤口感染的独立预测因素,CAD、COPD、术前血清白蛋白水平低和使用类固醇是住院时间延长的独立预测因素。因此,在进行腹壁疝修补术前,应考虑优化患者的心肺和营养状况。

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