Girotto John A, Chiaramonte Michael, Menon Nathan G, Singh Navin, Silverman Ron, Tufaro Anthony P, Nahabedian Maurice, Goldberg Nelson H, Manson Paul N
Division of Plastic, Reconstructive, and Maxillofacial Surgery, Department of Surgery, The Johns Hopkins School of Medicine, Baltimore, Md, USA.
Plast Reconstr Surg. 2003 Jul;112(1):106-14. doi: 10.1097/01.PRS.0000066162.18720.C8.
Secondary repair of recurrent ventral hernia is difficult, and success depends on re-establishing the functional integrity of the abdominal wall. Current techniques used for closure of these defects have documented recurrence rates as high as 54 percent. The authors' 8-year experience utilizing variations of the components separation technique for autologous tissue repair of recalcitrant hernias emphasizes that recurrent or recalcitrant hernias benefit from the creation of a dynamic abdominal wall. A total of 389 patients were retrospectively identified as having abdominal wall defects, and 284 of these patients met the selection criteria. Study patients were grouped according to the type of surgical repair used. The recurrence rate was 20.7 percent over all study groups and was directly related to the extent of repair required. Group 1 patients (wide tissue undermining) had a recurrence rate of only 15 percent, while in group 2 (complete components separation), the recurrence rate was 22 percent. Group 3 patients (interpositional fascia lata graft) had a 29 percent recurrence rate. Time to recurrence was also significantly different across treatment groups, with study group 3 experiencing earlier hernia recurrence. The most frequent postoperative complication was wound infection, which was directly related to the repair performed. The relative odds of recurrence versus the risk factors of age, sex, perioperative steroid use, wound infection, defect size, and the presence of enterocutaneous fistula were studied with a logistic regression analysis. These factors did not possess statistical significance for predicting hernia recurrence. The preoperative presence of mesh was independently significant for hernia recurrence, increasing the relative odds 2.2 times (p = 0.01). Similarly, when other risk factors were controlled for, increasing the complexity of the treatment group, from study group 1 (wide tissue undermining) to study group 3 (interpositional fascia lata graft), also increased the odds of hernia recurrence 1.5-fold per group (p = 0.04). Average inpatient cost was $24,488. The length of inpatient stay ranged from 2 to 172 days (average, 12.8 days). The length of inpatient stay and costs were directly related to the extent of repair required. Using the analysis of variance test for multiple factors, the presence of an enterocutaneous fistula (p = 0.0014) or a postoperative wound infection (p = 0.008) independently increased the length of inpatient stay and hospital costs. A total of 108 successfully repaired patients were contacted by telephone and agreed to participate in a self-reported satisfaction survey. The patients noticed improvements in the appearance of their abdomen, in their postoperative emotional state, and in their ability to lift objects, arise from a chair or a bed, and exercise. These results suggest that recalcitrant hernia defects should be solved, when possible, by reconstructing a dynamic abdominal wall.
复发性腹疝的二次修复难度较大,其成功与否取决于腹壁功能完整性的重建。目前用于闭合这些缺损的技术所记录的复发率高达54%。作者利用改良的成分分离技术对顽固性疝进行自体组织修复的8年经验强调,复发性或顽固性疝可通过构建动态腹壁而获益。共有389例患者经回顾性分析确定存在腹壁缺损,其中284例符合入选标准。研究患者根据所采用的手术修复类型进行分组。所有研究组的总复发率为20.7%,且与所需修复的范围直接相关。第1组患者(广泛组织潜行分离)的复发率仅为15%,而第2组(完全成分分离)的复发率为22%。第3组患者(阔筋膜移植)的复发率为29%。复发时间在各治疗组之间也存在显著差异,第3研究组疝复发较早。最常见的术后并发症是伤口感染,这与所进行的修复直接相关。通过逻辑回归分析研究了复发的相对比值与年龄、性别、围手术期使用类固醇、伤口感染、缺损大小以及肠皮肤瘘存在等风险因素之间的关系。这些因素对于预测疝复发不具有统计学意义。术前使用补片对于疝复发具有独立的显著影响,使相对比值增加2.2倍(p = 0.01)。同样,在控制其他风险因素后,从第1研究组(广泛组织潜行分离)到第3研究组(阔筋膜移植),治疗组复杂性增加,每组疝复发的几率也增加1.5倍(p = 0.04)。平均住院费用为24,488美元。住院时间从2天到172天不等(平均12.8天)。住院时间和费用与所需修复的范围直接相关。采用多因素方差分析,肠皮肤瘘的存在(p = 0.0014)或术后伤口感染(p = 0.008)独立增加了住院时间和住院费用。通过电话联系了108例成功修复的患者,他们同意参与一项自我报告的满意度调查。患者注意到腹部外观、术后情绪状态以及提举物品、从椅子或床上起身和锻炼能力等方面均有改善。这些结果表明,对于顽固性疝缺损,应尽可能通过重建动态腹壁来解决。