de Grey Aubrey D N J
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK.
Sci Aging Knowledge Environ. 2003 Jan 8;2003(1):VP1. doi: 10.1126/sageke.2003.1.vp1.
In this Viewpoint, I list the various age-related molecular and cellular changes that are thought to limit mammalian life-span, and I outline a problem-solving approach to reversing these detrimental changes. This approach should help to prevent the development of these age-related changes into life-threatening pathologies and possibly, in due course, allow a large increase in healthy human life expectancy.
在这篇观点文章中，我列出了各种被认为会限制哺乳动物寿命的与年龄相关的分子和细胞变化，并概述了一种解决问题的方法来逆转这些有害变化。这种方法应有助于防止这些与年龄相关的变化发展成危及生命的病症，并有可能在适当的时候大幅延长人类的健康预期寿命。
