Kararmaz A, Kaya S, Turhanoglu S, Ozyilmaz M A
Department of Anaesthesiology, Dicle University Hospital, 21280 Diyarbakir, Turkey.
Anaesthesia. 2003 Jun;58(6):526-30. doi: 10.1046/j.1365-2044.2003.03153.x.
We evaluated the effect of low-dose bupivacaine plus fentanyl administered intrathecally in elderly patients undergoing transurethral prostatectomy. Patients were randomly assigned to one of two groups. Group F received plain bupivacaine 4 mg with 25 micro g of fentanyl and sterile water to a total of 1.5 ml, and Group B received only 0.5% plain bupivacaine 7.5 mg for spinal anaesthesia. Sensory block was adequate for surgery in all patients. The mean level of motor block was higher and the duration of motor block was longer in Group B (p < 0.0001). Hypotension and shivering were significantly more common in Group B (p < 0.05). The addition of fentanyl 25 micro g to plain bupivacaine 4 mg provides adequate analgesia for transurethral prostatectomy with fewer side-effects in elderly patients when compared with the conventional dose of bupivacaine.
我们评估了鞘内注射低剂量布比卡因加芬太尼对接受经尿道前列腺切除术的老年患者的影响。患者被随机分为两组。F组接受4毫克布比卡因加25微克芬太尼及无菌水，总量为1.5毫升，B组仅接受0.5%布比卡因7.5毫克用于脊髓麻醉。所有患者的感觉阻滞均足以进行手术。B组的平均运动阻滞平面更高，运动阻滞持续时间更长（p<0.0001）。B组低血压和寒战明显更常见（p<0.05）。与传统剂量的布比卡因相比，在4毫克布比卡因中添加25微克芬太尼可为经尿道前列腺切除术提供足够的镇痛效果，且老年患者的副作用更少。
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