Riso Patrizia, Brusamolino Antonella, Ciappellano Salvatore, Porrini Marisa
Department of Food Science and Technology and Microbiology, Division of Human Nutrition-University of Milan, Milan, Italy.
Int J Vitam Nutr Res. 2003 May;73(3):201-5. doi: 10.1024/0300-9831.73.3.201.
Lutein is a carotenoid present in dark green leafy vegetables and it may be involved in the prevention of several diseases related to oxidative stress. The aim of this study was to evaluate bioavailability of lutein from different food sources (150 g spinach and 200 g broccoli) and a supplement in oil (300 mg VEGEX), all providing about 9 mg lutein. Eight healthy females were instructed to eat a low-carotenoid diet for the period of experimentation. On three different occasions, three weeks apart, volunteers ate the lutein sources together with 10 g olive oil and 40 g bread. Blood samples were collected just before eating, every two hours for 12 hours, and at 24, 32, 56, 80 and 104 hours. Lutein concentration increased significantly after six to eight hours and peaked after 10-12 hours, with the highest concentration reached after VEGEX intake. Lutein concentration remained significantly elevated for up to 80 hours (VEGEX and spinach). On the whole, our results suggest that the intake of one single dose of lutein from different sources is able to bring about a significant plasma response in the short term.
叶黄素是一种存在于深绿色叶菜中的类胡萝卜素，它可能参与预防多种与氧化应激相关的疾病。本研究的目的是评估来自不同食物来源（150克菠菜和200克西兰花）以及一种油剂补充剂（300毫克VEGEX）中叶黄素的生物利用度，所有这些来源提供的叶黄素约为9毫克。八名健康女性被要求在实验期间食用低类胡萝卜素饮食。在三个不同的场合，每次间隔三周，志愿者们将叶黄素来源与10克橄榄油和40克面包一起食用。在进食前、进食后每两小时共12小时以及在24、32、56、80和104小时采集血样。叶黄素浓度在6至8小时后显著增加，并在10 - 12小时达到峰值，VEGEX摄入后达到最高浓度。叶黄素浓度在长达80小时内（VEGEX和菠菜）仍显著升高。总体而言，我们的结果表明，从不同来源单次摄入叶黄素能够在短期内引起显著的血浆反应。
