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心肌性能指数(Tei指数)不能反映急性心肌梗死后左心室功能的长期变化。

Myocardial performance index (Tei index) does not reflect long-term changes in left ventricular function after acute myocardial infarction.

作者信息

Hole Torstein, Skaerpe Terje

机构信息

Section of Cardiology, Medical Department, Alesund Hospital, Norway.

出版信息

Echocardiography. 2003 Jan;20(1):1-7. doi: 10.1046/j.1540-8175.2003.00001.x.

DOI:10.1046/j.1540-8175.2003.00001.x
PMID:12848692
Abstract

AIMS

To evaluate whether changes in myocardial performance index (MPI or Tei index) were related to changes in other Doppler echocardiographic parameters after acute myocardial infarction, or had any independent prognostic impact in a 2-year observational study.

METHODS AND RESULTS

Seventy-one patients with acute myocardial infarction without heart failure were examined at baseline, 3 months, and 2 years. MPI was significantly related to end-diastolic and end-systolic volume indexes, ejection fraction, maximal velocity, and time velocity integral of early mitral filling wave at 3 months and 2 years. MPI did not contribute significantly to the prediction of any changes in the measures of diastolic or systolic function at 3 months or 2 years. Baseline MPI was significantly higher in patients who later developed heart failure(0.55 +/- 0.16)than in other patients(0.43 +/- 0.13, P = 0.006), but had no independent predictive power for the development of heart failure or death relative to end-systolic volume index and deceleration time of early mitral filling wave.

CONCLUSION

MPI did not accurately reflect changes in Doppler and two-dimensional echocardiographic measures of diastolic or systolic function during a 2-year follow-up after acute myocardial infarction, and did not have any independent prognostic impact.

摘要

目的

在一项为期2年的观察性研究中,评估急性心肌梗死后心肌性能指数(MPI或Tei指数)的变化是否与其他多普勒超声心动图参数的变化相关,或是否具有任何独立的预后影响。

方法与结果

对71例无心力衰竭的急性心肌梗死患者在基线、3个月和2年时进行检查。在3个月和2年时,MPI与舒张末期和收缩末期容积指数、射血分数、最大速度以及二尖瓣早期充盈波的时间速度积分显著相关。MPI对3个月或2年时舒张或收缩功能指标的任何变化预测均无显著贡献。后来发生心力衰竭的患者基线MPI(0.55±0.16)显著高于其他患者(0.43±0.13,P = 0.006),但相对于收缩末期容积指数和二尖瓣早期充盈波减速时间,对心力衰竭或死亡的发生没有独立的预测能力。

结论

在急性心肌梗死后2年的随访中,MPI不能准确反映舒张或收缩功能的多普勒和二维超声心动图测量变化,且没有任何独立的预后影响。

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