Roldan-Molina F, de Oliveira e Silva A, dos Santos T E, Genzini T, de Miranda M P, de Oliveira R M, Santo G C, D'Albuquerque L A
Hospital da Beneficência Portuguesa de São Paulo.
Arq Gastroenterol. 1992 Apr-Jun;29(2):56-61.
As a contribution to the study of ascites in patients with liver cirrhosis, congestive heart failure and peritoneal carcinomatosis evaluate in serum and ascites the concentrations of alphafetoprotein, carcinoembryonic antigen and fibronectin, they might suggest a diagnosis for the basic pathology. Forty-seven patients were studied, from whom 23 with cirrhosis, 17 peritoneal carcinomatosis and 7 with congestive heart failure. We conclude that: a) none of the tools usually employed in the analysis of ascitic fluid alone can make the base pathological process responsible for producing ascites; b) fibronectins were more useful for differential diagnosis between cirrhosis and carcinomatosis; c) alpha-fetoprotein and carcinoembryonic antigen were not useful for the definition for differential diagnosis.
为了对肝硬化、充血性心力衰竭和腹膜癌患者的腹水进行研究,我们检测了血清和腹水中甲胎蛋白、癌胚抗原和纤连蛋白的浓度,这些指标可能有助于对基础病理状况做出诊断。我们对47例患者进行了研究,其中23例为肝硬化患者,17例为腹膜癌患者,7例为充血性心力衰竭患者。我们得出以下结论:a)仅靠分析腹水时常用的任何一项指标都无法确定导致腹水的基础病理过程;b)纤连蛋白在肝硬化和癌病的鉴别诊断中更有用;c)甲胎蛋白和癌胚抗原对鉴别诊断的定义没有帮助。