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城市人群中代谢综合征的患病率:德黑兰血脂与血糖研究

Prevalence of metabolic syndrome in an urban population: Tehran Lipid and Glucose Study.

作者信息

Azizi Fereidoun, Salehi Payam, Etemadi Arash, Zahedi-Asl Saleh

机构信息

Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, P.O. Box 4763, Tehran 19395, Iran.

出版信息

Diabetes Res Clin Pract. 2003 Jul;61(1):29-37. doi: 10.1016/s0168-8227(03)00066-4.

Abstract

The aim of the present investigation was to determine the prevalence of the metabolic syndrome among 103,68 of the adults (4,397 men and 5,971 women) aged 20 years and over, participating in the Tehran Lipid and Glucose Study. The metabolic syndrome was defined by the presence of three or more of the following components: abdominal obesity, hypertriglyceridemia, low HDL-C, high blood pressure, and high fasting glucose. The unadjusted prevalence of metabolic syndrome in the study population was 30.1% (CI 95%: 29.2-31.0) and age-standardized prevalence was 33.7% (CI 95%: 32.8-34.6). The prevalence increased with age in both sexes. The metabolic syndrome was more commonly seen in women than in men (42% vs. 24%, P<0.001). Low HDL-C was the most common metabolic abnormality in both sexes. Except for high FPG, all abnormalities were more common in women than in men (P<0.001). Most of those with metabolic syndrome had three components of the syndrome (58%), 33% had four, and 9% had five components. This report on the metabolic syndrome from Iran shows a high prevalence of this disorder. Efforts on promoting healthy diets, physical activity, and blood pressure control must be undertaken.

摘要

本研究的目的是确定参与德黑兰血脂与血糖研究的10368名20岁及以上成年人(4397名男性和5971名女性)中代谢综合征的患病率。代谢综合征的定义为存在以下三种或更多组分:腹型肥胖、高甘油三酯血症、低高密度脂蛋白胆固醇、高血压和空腹血糖升高。研究人群中代谢综合征的未调整患病率为30.1%(95%CI:29.2 - 31.0),年龄标准化患病率为33.7%(95%CI:32.8 - 34.6)。患病率在两性中均随年龄增长而升高。代谢综合征在女性中比在男性中更常见(42%对24%,P<0.001)。低高密度脂蛋白胆固醇是两性中最常见的代谢异常。除空腹血糖升高外,所有异常在女性中比在男性中更常见(P<0.001)。大多数患有代谢综合征的人有该综合征的三个组分(58%),33%有四个组分,9%有五个组分。这份来自伊朗的关于代谢综合征的报告显示该疾病的患病率很高。必须努力促进健康饮食、体育活动和血压控制。

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