Satyarthee G D, Mahapatra A K
The Department of Neurosurgery, All India Institute of Medical sciences, New Delhi, India.
J Clin Neurosci. 2003 Jul;10(4):497-9. doi: 10.1016/s0967-5868(02)00285-0.
Tuberculoma involving the sellar and suprasellar region is extremely rare. Sellar region tuberculoma usually presents with endocrinopathy of hypofunction, rarely hyperfunction or normal function of the anterior pituitary. However, sellar-suprasellar tuberculoma presenting with diabetes insipidus (DI) is very rare. We report the case of a 32 year old housewife presenting with DI and secondary amenorrhea, who had a sellar-suprasellar mass on MRI. She underwent a transnasal transsphenoidal surgical removal of the pituitary mass, which was tubercular in nature on histology. She received antitubercular treatment and hormonal replacement therapy. She was well at last follow-up, 3 years after surgery.
累及鞍区和鞍上区域的结核瘤极为罕见。鞍区结核瘤通常表现为垂体功能减退的内分泌病，很少出现垂体前叶功能亢进或功能正常的情况。然而，以尿崩症（DI）为表现的鞍上结核瘤非常罕见。我们报告一例32岁家庭主妇，表现为尿崩症和继发性闭经，磁共振成像（MRI）显示鞍上有肿块。她接受了经鼻蝶窦垂体肿块手术切除，组织学检查显示肿块为结核性质。她接受了抗结核治疗和激素替代治疗。术后3年最后一次随访时她情况良好。
