Black Jed
Stanford University Sleep Research Center, 401 Quarry Road, 3301, Stanford, CA 94305, USA.
Respir Physiol Neurobiol. 2003 Jul 16;136(2-3):211-20. doi: 10.1016/s1569-9048(03)00083-1.
Sleepiness is a common, but not necessary symptom of the obstructive sleep apnea syndrome (OSA) and is a frequent chief complaint of patients with OSA who seek medical attention. While sleepiness may seem simple in nature, the underlying mechanisms producing daytime sleepiness in OSA are complex and poorly characterized. Moreover, the meaningful assessment of pathological sleepiness is frequently far from straightforward. Effective treatment of OSA is generally expected to resolve or ameliorate daytime sleepiness. An unknown percentage of treated OSA patients, however, remain sleepy during waking hours. The assessment and treatment of residual sleepiness in treated OSA can range from simple to difficult, depending on the nature and causes of the continued sleepiness. Recently, however, data from clinical trials have been generated which provide direction in the evaluation and management of the OSA patient suffering residual daytime sleepiness.
嗜睡是阻塞性睡眠呼吸暂停综合征（OSA）常见但并非必然出现的症状，也是寻求医疗关注的OSA患者常见的主要诉求。虽然嗜睡本质上看似简单，但OSA导致日间嗜睡的潜在机制复杂且特征不明。此外，对病理性嗜睡进行有意义的评估往往并非易事。一般认为，有效治疗OSA有望解决或改善日间嗜睡问题。然而，仍有未知比例的接受治疗的OSA患者在清醒时仍感困倦。治疗后OSA患者残留嗜睡的评估和治疗难度不一，这取决于持续嗜睡的性质和原因。不过，最近来自临床试验的数据为评估和管理仍有日间残留嗜睡的OSA患者提供了指导方向。
