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Immunotoxins to human small-cell lung cancer.

作者信息

Wawrzynczak E J, Derbyshire E J

机构信息

Drug Targeting Laboratory, Institute of Cancer Research, Sutton, Surrey, UK.

出版信息

Cell Biophys. 1992 Aug-Dec;21(1-3):13-23. doi: 10.1007/BF02789474.

Abstract

Ricin A chain ITs directed against a variety of the common cell-surface antigens associated with SCLC exerted selective toxic effects on SCLC cell lines. The potency of the cytotoxic effects matched or exceeded that previously reported for ricin A chain ITs directed against identical or similar antigens on other types of carcinoma, suggesting that SCLC may be uniquely sensitive to this type of IT.

摘要

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