Loebe M, Hetzer R, Schüler S, Hummel M, Friedel N, Weng Y, Schiessler A
Deutsches Herzzentrum Berlin.
Zentralbl Chir. 1992;117(12):681-8.
Heart transplantation has become a standard procedure in the treatment for irreversible heart failure. Criteria for both recipients and donors have been extended. One year survival now reaches 81%. In the immediate postoperative course patients are endangered by infection. In the long-term course coronary artery disease of the transplanted heart becomes the most serious problem. Alteration of liver and kidney function due to chronic medication as well as malignancies and hypertension also occur. In case of chronic transplant failure retransplantation may be indicated. Acute cardiac failure before transplantation nowerdays can be treated by mechanical circulatory assist devices.
心脏移植已成为治疗不可逆性心力衰竭的标准手术。受体和供体的标准都有所扩展。目前一年生存率达到81%。术后即刻，患者受到感染的威胁。在长期过程中，移植心脏的冠状动脉疾病成为最严重的问题。长期用药导致的肝肾功能改变以及恶性肿瘤和高血压也会出现。如果发生慢性移植失败，可能需要再次移植。如今，移植前的急性心力衰竭可用机械循环辅助装置治疗。
