Davis Edward G, MacKenzie Ellen J, Sacco William J, Bain Lawrence W, Buckman Robert F, Champion Howard R, Lees Peter S J
Bloomberg School of Public Health, Department of Environmental Health Sciences, Johns Hopkins University, Baltimore, MD, USA.
J Trauma. 2003 Jul;55(1):53-61. doi: 10.1097/01.TA.0000075340.22097.B5.
Prehospital trauma patient field intubations and paralyzations, using neuromuscular blocking agents before emergency department respiratory and neurologic assessments are made, bias assessments and outcome evaluations using probability-of-survival models, such as TRISS and A Severity Characterization of Trauma (ASCOT). We present a newly developed "TRISS-like" probability-of-survival model for intubated blunt- and penetrating-injured patient assessment.
From a population of 51397 consecutively admitted trauma patients, this study used all 5740 (11.2% of the total injured population) intubated patients with complete data from a statewide trauma registry from October 1, 1993, to September 30, 1996. Model performance was evaluated using standard calibration and discrimination measures and z and W statistics of significance.
The new model accurately predicted survival for blunt- and penetrating-injured intubated patients and is applicable to 11 etiologic patient populations.
Study findings suggest that the new TRISS-like model should be used to assess both blunt- and penetrating-injured intubated patients. Use of this new model provides an analytical method for addressing a significant limitation of both the standard TRISS and ASCOT models, which are not applicable to intubated injured patient assessment. In addition, use of this model will complement TRISS/ASCOT assessments of nonintubated trauma patients and thus permit appropriate assessments for both intubated and nonintubated injured patient study populations.
在急诊部门进行呼吸和神经学评估之前,对院前创伤患者进行现场插管和使用神经肌肉阻滞剂进行麻痹,会使使用生存概率模型(如TRISS和创伤严重程度特征化评分(ASCOT))的评估和结果评价产生偏差。我们提出了一种新开发的“类TRISS”生存概率模型,用于评估插管的钝性和穿透性损伤患者。
本研究从51397例连续入院的创伤患者中选取了1993年10月1日至1996年9月30日期间全州创伤登记处所有5740例(占受伤总人数的11.2%)有完整数据的插管患者。使用标准校准和鉴别测量以及z和W显著性统计量对模型性能进行评估。
新模型准确预测了插管的钝性和穿透性损伤患者的生存情况,适用于11种病因的患者群体。
研究结果表明,新的类TRISS模型应用于评估插管的钝性和穿透性损伤患者。使用该新模型提供了一种分析方法,以解决标准TRISS和ASCOT模型的一个重大局限性,即它们不适用于插管受伤患者的评估。此外,使用该模型将补充对非插管创伤患者的TRISS/ASCOT评估,从而允许对插管和非插管受伤患者研究群体进行适当评估。