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格雷夫斯病合并抗心磷脂抗体阳性及获得性蛋白S缺乏症。

Graves' disease associated with anticardiolipin antibody positivity and acquired protein S deficiency.

作者信息

Nakayama Tomohiro, Yamamoto Tatsuo, Kanmatsuse Katsuo, Kokubun Shinichiro

机构信息

Division of Receptor Biology, Advanced Medical Research Center, Nihon University School of Medicine, Ooyaguchi-kamimachi 30-1, Itabashi-ku, Tokyo 173-8610, Japan.

出版信息

Rheumatol Int. 2003 Jul;23(4):198-200. doi: 10.1007/s00296-003-0291-6. Epub 2003 Feb 26.

DOI:10.1007/s00296-003-0291-6
PMID:12856147
Abstract

A 33-year-old woman had experienced recurrent pregnancy loss. She had positive anticardiolipin antibody and protein S deficiency. Her pregnancy was managed with anticoagulant therapy and she delivered a healthy infant. Three years after delivery, she reported progressive sweating, tremor, tachycardia, and a 4-kg weight loss. She was diagnosed with Graves' disease. This is a rare case of combined anticardiolipin antibody positivity, acquired protein S deficiency, and Graves' disease.

摘要

一名33岁女性曾经历反复流产。她抗心磷脂抗体呈阳性且存在蛋白S缺乏。她的孕期采用抗凝治疗，最终产下一名健康婴儿。分娩三年后，她出现进行性多汗、震颤、心动过速以及体重减轻4千克的情况。她被诊断为格雷夫斯病。这是一例抗心磷脂抗体阳性、获得性蛋白S缺乏与格雷夫斯病并存的罕见病例。

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Rheumatol Int. 2003 Jul;23(4):198-200. doi: 10.1007/s00296-003-0291-6. Epub 2003 Feb 26.
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本文引用的文献

1
Herbal factors in the treatment of autoimmunity-related habitual abortion.治疗自身免疫性习惯性流产的草药因素。
Vitam Horm. 2002;65:333-44. doi: 10.1016/s0083-6729(02)65070-8.
2
Herbal medicines, Sairei-to and Tokishakuyaku-san, differently modulate the release of cytokines from decidual versus peripheral blood mononuclear cells.
Am J Reprod Immunol. 2001 Nov;46(5):369-72. doi: 10.1034/j.1600-0897.2001.d01-26.x.
3
Association of the HLA-DRB1*0301 and HLA-DQA1*0501 alleles with Graves' disease in a population representing the gene contribution from several ethnic backgrounds.在一个代表多个种族背景基因贡献的人群中，HLA - DRB1*0301和HLA - DQA1*0501等位基因与格雷夫斯病的关联。
Thyroid. 2001 Jan;11(1):31-5. doi: 10.1089/10507250150500630.
4
Theoretical basis for herbal medicines, Tokishakuyaku-san and Sairei-to, in the treatment of autoimmunity-related recurrent abortion by correcting T helper-1/T helper-2 balance.中药芍药甘草汤和柴苓汤通过纠正辅助性T细胞1/辅助性T细胞2平衡治疗自身免疫性复发性流产的理论基础。
Am J Reprod Immunol. 2000 Dec;44(6):342-6. doi: 10.1111/j.8755-8920.2000.440604.x.
5
Primary role of the HLA class II DRB1*0301 allele in Graves disease.
Am J Med Genet. 2000 Dec 18;95(5):432-7. doi: 10.1002/1096-8628(20001218)95:5<432::aid-ajmg5>3.0.co;2-7.
6
HLA associations of anti-beta2 glycoprotein I response in a Greek cohort with antiphospholipid syndrome and meta-analysis of four ethnic groups.
Hum Immunol. 1999 Dec;60(12):1274-80. doi: 10.1016/s0198-8859(99)00122-6.
7
Enhancement of protein S anticoagulant function by beta2-glycoprotein I, a major target antigen of antiphospholipid antibodies: beta2-glycoprotein I interferes with binding of protein S to its plasma inhibitor, C4b-binding protein.
Thromb Haemost. 1999 May;81(5):748-57.
8
Associations of anti-beta2-glycoprotein I autoantibodies with HLA class II alleles in three ethnic groups.三个种族群体中抗β2-糖蛋白I自身抗体与HLA II类等位基因的关联。
Arthritis Rheum. 1999 Feb;42(2):268-74. doi: 10.1002/1529-0131(199902)42:2<268::AID-ANR8>3.0.CO;2-K.
9
Studies on associations between human leukocyte antigen (HLA) class II alleles and antiphospholipid antibodies in Danish and Czech women with recurrent miscarriages.丹麦和捷克复发性流产女性中人类白细胞抗原（HLA）II类等位基因与抗磷脂抗体之间关联的研究。
Hum Reprod. 1998 Dec;13(12):3326-31. doi: 10.1093/humrep/13.12.3326.
10
Protein S deficiency and pregnancy: is there a case for ylaxis?蛋白S缺乏与妊娠：是否有进行预防的情况？
Minerva Ginecol. 1997 Oct;49(10):447-8.