Nakayama Tomohiro, Yamamoto Tatsuo, Kanmatsuse Katsuo, Kokubun Shinichiro
Division of Receptor Biology, Advanced Medical Research Center, Nihon University School of Medicine, Ooyaguchi-kamimachi 30-1, Itabashi-ku, Tokyo 173-8610, Japan.
Rheumatol Int. 2003 Jul;23(4):198-200. doi: 10.1007/s00296-003-0291-6. Epub 2003 Feb 26.
A 33-year-old woman had experienced recurrent pregnancy loss. She had positive anticardiolipin antibody and protein S deficiency. Her pregnancy was managed with anticoagulant therapy and she delivered a healthy infant. Three years after delivery, she reported progressive sweating, tremor, tachycardia, and a 4-kg weight loss. She was diagnosed with Graves' disease. This is a rare case of combined anticardiolipin antibody positivity, acquired protein S deficiency, and Graves' disease.
一名33岁女性曾经历反复流产。她抗心磷脂抗体呈阳性且存在蛋白S缺乏。她的孕期采用抗凝治疗,最终产下一名健康婴儿。分娩三年后,她出现进行性多汗、震颤、心动过速以及体重减轻4千克的情况。她被诊断为格雷夫斯病。这是一例抗心磷脂抗体阳性、获得性蛋白S缺乏与格雷夫斯病并存的罕见病例。