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Animal models of tinnitus.

作者信息

Bauer Carol A

机构信息

Division of Otolaryngology, Southern Illinois University School of Medicine, PO Box 19662, Springfield, IL 62794-9662, USA.

出版信息

Otolaryngol Clin North Am. 2003 Apr;36(2):267-85, vi. doi: 10.1016/s0030-6665(02)00171-8.

DOI:10.1016/s0030-6665(02)00171-8
PMID:12856296
Abstract

Tinnitus is a complex phenomenon that is poorly understood. A significant tool for studying the pathophysiology of tinnitus and exploring potential treatments is an animal model. This article discusses the general techniques for evaluating psychophysical phenomenon in nonhuman subjects. An overview of a model of chronic tinnitus in rats and chinchillas is presented.

摘要

相似文献

1
Animal models of tinnitus.
Otolaryngol Clin North Am. 2003 Apr;36(2):267-85, vi. doi: 10.1016/s0030-6665(02)00171-8.
2
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Vigabatrin, a GABA transaminase inhibitor, reversibly eliminates tinnitus in an animal model.氨己烯酸，一种γ-氨基丁酸转氨酶抑制剂，能在动物模型中可逆地消除耳鸣。
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Tinnitus and neural activity.耳鸣与神经活动。
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A Conditioned Behavioral Paradigm for Assessing Onset and Lasting Tinnitus in Rats.一种用于评估大鼠耳鸣发作和持续性耳鸣的条件性行为范式。
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引用本文的文献

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Does alleviate tinnitus? A review of the current literature.是否能缓解耳鸣？当前文献综述。
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Acoustic Trauma Changes the Parvalbumin-Positive Neurons in Rat Auditory Cortex.
声创伤改变大鼠听觉皮层中的钙结合蛋白阳性神经元。
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Behavioral and neural discrimination of speech sounds after moderate or intense noise exposure in rats.大鼠在中度或强烈噪声暴露后对语音声音的行为和神经辨别
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Methodological aspects of clinical trials in tinnitus: a proposal for an international standard.耳鸣临床试验的方法学方面：国际标准建议。
J Psychosom Res. 2012 Aug;73(2):112-21. doi: 10.1016/j.jpsychores.2012.05.002. Epub 2012 Jun 22.
6
Tracking the expression of excitatory and inhibitory neurotransmission-related proteins and neuroplasticity markers after noise induced hearing loss.追踪噪声性听力损失后兴奋性和抑制性神经递质相关蛋白及神经可塑性标志物的表达。
PLoS One. 2012;7(3):e33272. doi: 10.1371/journal.pone.0033272. Epub 2012 Mar 12.
7
Tuning out the noise: limbic-auditory interactions in tinnitus.调谐出噪声：耳鸣的边缘听觉相互作用。
Neuron. 2010 Jun 24;66(6):819-26. doi: 10.1016/j.neuron.2010.04.032.
8
Vigabatrin, a GABA transaminase inhibitor, reversibly eliminates tinnitus in an animal model.氨己烯酸，一种γ-氨基丁酸转氨酶抑制剂，能在动物模型中可逆地消除耳鸣。
J Assoc Res Otolaryngol. 2007 Mar;8(1):105-18. doi: 10.1007/s10162-006-0067-2. Epub 2007 Jan 13.