A quantitative model of ligand binding to the glutamate site of the GluR2 subunit of AMPA receptor.

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作者信息

Tikhonova I G, Baskin I I, Palyulin V A, Zefirov N S

机构信息

Moscow State University, Vorob'evy gory, Moscow, 119992 Russia.

出版信息

Dokl Biochem Biophys. 2003 Mar-Apr;389:75-8. doi: 10.1023/a:1023623803790.

DOI:10.1023/a:1023623803790

PMID:12856409

Abstract

摘要

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Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins.比较分子场分析（CoMFA）。1. 形状对类固醇与载体蛋白结合的影响。

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8-(1H-imidazol-1-yl)-7-nitro-4(5H)-imidazo[1,2-alpha]quinoxalinone and related compounds: synthesis and structure-activity relationships for the AMPA-type non-NMDA receptor.8-（1H-咪唑-1-基）-7-硝基-4（5H）-咪唑并[1,2-α]喹喔啉酮及相关化合物：AMPA型非NMDA受体的合成与构效关系

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Novel AMPA receptor antagonists: synthesis and structure-activity relationships of 1-hydroxy-7-(1H-imidazol-1-yl)-6-nitro-2,3(1H,4H)- quinoxalinedione and related compounds.新型AMPA受体拮抗剂：1-羟基-7-(1H-咪唑-1-基)-6-硝基-2,3(1H,4H)-喹喔啉二酮及相关化合物的合成与构效关系

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Mutations in a putative agonist binding region of the AMPA-selective glutamate receptor channel.

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