Nuttin Bart J, Gabriels Loes, van Kuyck Kris, Cosyns Paul
Department of Neurosurgery, Katholieke Universiteit Leuven, University Hospitals Leuven, Herestraat 49, B-3000, Leuven, Belgium.
Neurosurg Clin N Am. 2003 Apr;14(2):267-74. doi: 10.1016/s1042-3680(02)00117-1.
Anterior capsular stimulation induces some improvement in severe treatment-resistant OCD patients. At this stage, not all stimulation-induced effects can be explained. The effects are a valuable source for further neurophysiologic and neuroanatomic research. It was reassuring that when the group of Drs Rasmussen, Greenberg, and Friehs in Providence and the group of Drs Rezai, Montgomery, and Malone in Cleveland started to operate on OCD patients using exactly the same technique, similar effects were seen in the patients. The authors still want to stress that anterior capsular stimulation remains investigational and needs optimization, especially to try to solve the problem of the short battery life of the stimulators.
前囊刺激可使重度难治性强迫症患者有一定程度的改善。现阶段,并非所有刺激诱导的效应都能得到解释。这些效应是进一步进行神经生理学和神经解剖学研究的宝贵资源。令人欣慰的是,普罗维登斯的拉斯穆森博士、格林伯格博士和弗里希斯博士团队与克利夫兰的雷扎伊博士、蒙哥马利博士和马龙博士团队开始使用完全相同的技术对强迫症患者进行手术时,在患者身上观察到了相似的效果。作者仍想强调,前囊刺激仍处于研究阶段,需要优化,特别是要努力解决刺激器电池续航时间短的问题。