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[缺血性心脏病危险因素在心脏X综合征发病机制中的作用]

[The role of ischemic heart disease risk factors in pathogenesis of cardiological syndrome X].

作者信息

Kostin V I, Likhomanov K S

出版信息

Klin Med (Mosk). 2003;81(5):30-2.

Abstract

To specify lipid and carbohydrate metabolisms, coagulation and platelet hemostasis and their relationships with impairment of coronary circulation in patients with cardiological syndrome X (SX), we examined 204 SX patients and 31 controls. Compared to the controls, examinees with SX had signs of hyperinsulinemia, high levels of LDLP cholesterol, VLDLP cholesterol, atherogenic index, packed cell volume, fibrinogen and platelet aggregation. We found a positive correlation between the level of LDLP cholesterol, severity of hyperinsulinemia and maximal depression of ST wave in the course of bicycle exercise. There was no correlation between hemostasis parameters and the degree of ST depression.

摘要

为明确心脏X综合征(SX)患者的脂质和碳水化合物代谢、凝血及血小板止血情况,以及它们与冠脉循环受损之间的关系,我们对204例SX患者和31例对照者进行了检查。与对照组相比,SX受检者有高胰岛素血症迹象,低密度脂蛋白颗粒胆固醇、极低密度脂蛋白颗粒胆固醇、致动脉粥样硬化指数、红细胞压积、纤维蛋白原和血小板聚集水平较高。我们发现,在自行车运动过程中,低密度脂蛋白颗粒胆固醇水平、高胰岛素血症严重程度与ST段最大压低之间存在正相关。止血参数与ST段压低程度之间无相关性。

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