心脏X综合征中的运动耐量与高胰岛素血症

Exercise tolerance and hyperinsulinemia in cardiac syndrome X.

作者信息

Kolasilska-Kloch Władysława, Leśniak Wiktoria, Leszczyńska-Gołabek Iwona, Kieć-Wilk Beata, Kloch Małgorzata

机构信息

II Klinika Kardiologii Instytutu Kardiologii, Collegium Medicum Uniwersytetu Jagiellońskiego.

出版信息

Folia Med Cracov. 2004;45(1-2):13-23.

PMID:16276822

Abstract

The aim of the study was to evaluate the relationship between exercise tolerance, glucose and insulin levels and biochemical parameters related to endothelial function [endothelin-1 (ET-1), nitrite/nitrate (NOx)] in patients with cardiological syndrome X in comparison with healthy volunteers. The decrease of NOx level and NOx / ET-1 ratio suggests that endothelial dysfunction is present in cardiological syndrome X. Exercise tolerance correlated positively with NOx and negatively with insulin concentrations.

摘要

本研究的目的是评估心脏X综合征患者与健康志愿者相比，运动耐量、血糖和胰岛素水平以及与内皮功能相关的生化参数[内皮素-1 (ET-1)、亚硝酸盐/硝酸盐(NOx)]之间的关系。NOx水平和NOx/ET-1比值的降低表明心脏X综合征存在内皮功能障碍。运动耐量与NOx呈正相关，与胰岛素浓度呈负相关。