丙硫氧嘧啶（PTU）诱发的血管炎，与抗髓过氧化物酶抗中性粒细胞抗体（MPO-ANCA）相关。
Propylthiouracil (PTU)-induced vasculitis associated with antineutrophil antibody against myeloperoxidase (MPO-ANCA).
作者信息
Nakamori Yoshitaka, Tominaga Takayuki, Inoue Yasushi, Shinohara Kenji
机构信息
Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital, Hofu 747-8511.
出版信息
Intern Med. 2003 Jun;42(6):529-33. doi: 10.2169/internalmedicine.42.529.
A 54-year-old woman had been administered propylthiouracil (PTU) for Graves' disease for 4 years. Recently, she complained of hemoptysis due to pulmonary alveolar hemorrhage causing anemia, and also had microhematuria. Antineutrophil cytoplasmic antibody against myeloperoxidase (MPO-ANCA) was positive, and she was diagnosed with PTU-induced vasculitis. Cessation of PTU and the administration of corticosteroids ameliorated these manifestations.
一名54岁女性因格雷夫斯病服用丙硫氧嘧啶（PTU）4年。最近，她因肺泡出血导致贫血而出现咯血，并且还有镜下血尿。抗髓过氧化物酶中性粒细胞胞浆抗体（MPO-ANCA）呈阳性，她被诊断为PTU诱发的血管炎。停用PTU并给予皮质类固醇后，这些症状得到改善。
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