• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

丙硫氧嘧啶(PTU)诱发的血管炎,与抗髓过氧化物酶抗中性粒细胞抗体(MPO-ANCA)相关。

Propylthiouracil (PTU)-induced vasculitis associated with antineutrophil antibody against myeloperoxidase (MPO-ANCA).

作者信息

Nakamori Yoshitaka, Tominaga Takayuki, Inoue Yasushi, Shinohara Kenji

机构信息

Division of Hematology, Department of Medicine, Yamaguchi Prefecture Central Hospital, Hofu 747-8511.

出版信息

Intern Med. 2003 Jun;42(6):529-33. doi: 10.2169/internalmedicine.42.529.

DOI:10.2169/internalmedicine.42.529
PMID:12857055
Abstract

A 54-year-old woman had been administered propylthiouracil (PTU) for Graves' disease for 4 years. Recently, she complained of hemoptysis due to pulmonary alveolar hemorrhage causing anemia, and also had microhematuria. Antineutrophil cytoplasmic antibody against myeloperoxidase (MPO-ANCA) was positive, and she was diagnosed with PTU-induced vasculitis. Cessation of PTU and the administration of corticosteroids ameliorated these manifestations.

摘要

一名54岁女性因格雷夫斯病服用丙硫氧嘧啶(PTU)4年。最近,她因肺泡出血导致贫血而出现咯血,并且还有镜下血尿。抗髓过氧化物酶中性粒细胞胞浆抗体(MPO-ANCA)呈阳性,她被诊断为PTU诱发的血管炎。停用PTU并给予皮质类固醇后,这些症状得到改善。

相似文献

1
Propylthiouracil (PTU)-induced vasculitis associated with antineutrophil antibody against myeloperoxidase (MPO-ANCA).丙硫氧嘧啶(PTU)诱发的血管炎,与抗髓过氧化物酶抗中性粒细胞抗体(MPO-ANCA)相关。
Intern Med. 2003 Jun;42(6):529-33. doi: 10.2169/internalmedicine.42.529.
2
Frequency of appearance of myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) in Graves' disease patients treated with propylthiouracil and the relationship between MPO-ANCA and clinical manifestations.丙硫氧嘧啶治疗的格雷夫斯病患者中髓过氧化物酶抗中性粒细胞胞浆抗体(MPO-ANCA)的出现频率及MPO-ANCA与临床表现的关系。
Clin Endocrinol (Oxf). 2001 May;54(5):651-4. doi: 10.1046/j.1365-2265.2001.01282.x.
3
The onset of antineutrophil cytoplasmic antibody-associated vasculitis immediately after methimazole was switched to propylthiouracil in a woman with Graves' disease who wished to become pregnant.一位患有 Graves 病并希望怀孕的女性在将甲巯咪唑换用丙硫氧嘧啶后,立即出现抗中性粒细胞胞质抗体相关性血管炎。
Endocr J. 2013;60(3):383-8. doi: 10.1507/endocrj.ej12-0212. Epub 2012 Nov 16.
4
Propylthiouracil associated antineutrophil cytoplasmic antibodies (ANCA) in patients with childhood onset Graves' disease.儿童期发病的格雷夫斯病患者中丙硫氧嘧啶相关的抗中性粒细胞胞浆抗体(ANCA)
J Pediatr Endocrinol Metab. 2008 Jun;21(6):539-43.
5
Follow-up of avidity and titre of anti-myeloperoxidase antibodies in sera from patients with propylthiouracil-induced vasculitis.丙硫氧嘧啶诱发血管炎患者血清中抗髓过氧化物酶抗体亲和力和滴度的随访
Clin Endocrinol (Oxf). 2007 Apr;66(4):543-7. doi: 10.1111/j.1365-2265.2007.02770.x.
6
Clinical Characteristics and Outcomes of Propylthiouracil-Induced Antineutrophil Cytoplasmic Antibody-Associated Vasculitis in Patients with Graves' Disease: A Median 38-Month Retrospective Cohort Study from a Single Institution in China.中国单中心回顾性队列研究:丙硫氧嘧啶诱导的 Graves 病患者抗中性粒细胞胞浆抗体相关性血管炎的临床特征和转归:中位随访 38 个月。
Thyroid. 2017 Dec;27(12):1469-1474. doi: 10.1089/thy.2017.0468.
7
Treatment with propylthiouracil is associated with appearance of antineutrophil cytoplasmic antibodies in some patients with Graves' disease.在一些格雷夫斯病患者中,丙硫氧嘧啶治疗与抗中性粒细胞胞浆抗体的出现有关。
Thyroid. 2000 Jul;10(7):595-9. doi: 10.1089/thy.2000.10.595.
8
Serum anti-myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA) in patients with Graves' disease receiving anti-thyroid medication.接受抗甲状腺药物治疗的格雷夫斯病患者的血清抗髓过氧化物酶抗中性粒细胞胞浆抗体(MPO-ANCA)
Intern Med. 2003 Jun;42(6):463-4. doi: 10.2169/internalmedicine.42.463.
9
High prevalence of antineutrophil cytoplasmic antibody positivity in childhood onset Graves' disease treated with propylthiouracil.在接受丙硫氧嘧啶治疗的儿童期发病的格雷夫斯病中抗中性粒细胞胞浆抗体阳性的高患病率。
J Clin Endocrinol Metab. 2000 Nov;85(11):4270-3. doi: 10.1210/jcem.85.11.7000.
10
A long-term follow-up of serum myeloperoxidase antineutrophil cytoplasmic antibodies (MPO-ANCA) in patients with Graves disease treated with propylthiouracil.甲巯咪唑治疗 Graves 病患者的血清髓过氧化物酶抗中性粒细胞胞质抗体(MPO-ANCA)的长期随访。
Endocr J. 2010;57(1):73-9. doi: 10.1507/endocrj.k09e-230. Epub 2009 Oct 23.

引用本文的文献

1
A CASE REPORT OF HAND AND FOOT SKIN CHANGES RESEMBLING PTU-INDUCED VASCULITIS IN A YOUNG MALE WITH DIFFUSE TOXIC GOITRE.一例弥漫性毒性甲状腺肿青年男性手足皮肤改变酷似丙硫氧嘧啶所致血管炎的病例报告
Acta Endocrinol (Buchar). 2023 Jul-Sep;19(3):380-385. doi: 10.4183/aeb.2023.380. Epub 2024 Feb 1.
2
Necrotizing vasculitis as a complication of propylthiouracil.丙硫氧嘧啶致坏死性血管炎一例
West J Emerg Med. 2008 Nov;9(4):212-5.