Andrianakos Alexandros, Trontzas Panagiotis, Christoyannis Fotis, Dantis Petros, Voudouris Costas, Georgountzos Athanasios, Kaziolas George, Vafiadou Elizabeth, Pantelidou Kyriaki, Karamitsos Dimitrios, Kontelis Leonidas, Krachtis Petros, Nikolia Zouboulio, Kaskani Evaggelia, Tavaniotou Elpiniki, Antoniades Christos, Karanikolas George, Kontoyanni Anastasia
Rheumatic Disease Epidemiology Section, Hellenic Foundation for Rheumatological Research, Athens, Greece.
J Rheumatol. 2003 Jul;30(7):1589-601.
To assess the prevalence of rheumatic diseases in Greek urban, suburban, and rural adult general populations.
This cross-sectional population based epidemiological study of rheumatic diseases in Greece (the ESORDIG Study) was conducted on the total adult population of 2 urban, one suburban, and 4 rural communities (8547 subjects), as well as on 2100 out of 5686 randomly selected subjects in one suburban and one rural community. The study, based on a standardized questionnaire and clinical evaluation and laboratory investigation when necessary, was carried out by rheumatologists who visited the target population at their homes. Either established classification criteria or criteria set for the purposes of the study were used for diagnosis.
A total of 8740 subjects participated in the study (response rate 82.1%). The overall age and sex adjusted prevalence (prevalence(asa)) of rheumatic diseases in the total target adult population was 26.9% (95% CI 26.2-27.6), being significantly higher among women (33.7%) than men (19.9%) (p < 0.0005). Disease prevalence(asa) increased significantly with age (p < 0.0005). The most common disease group was low back pain, with a prevalence(asa) of 11.0%, followed by symptomatic peripheral osteoarthritis (7.9%), neck pain (4.8%), miscellaneous rheumatic disorders (4.4%), soft tissue rheumatism disorders (4.3%), and inflammatory rheumatic disease (2.1%). Logistic regression analysis showed a significant positive association of female or male sex, age >or= 50 years, high body mass index, low level of education, moderate or heavy alcohol consumption, and high socioeconomic level with particular diseases or disease groups.
These findings indicate rheumatic diseases are very common in the general adult population of Greece; 26.9% of adults currently have active or chronic rheumatic disease in remission.
评估希腊城市、郊区和农村成年普通人群中风湿性疾病的患病率。
这项针对希腊风湿性疾病的基于人群的横断面流行病学研究（ESORDIG研究），对2个城市、1个郊区和4个农村社区的全部成年人口（8547名受试者），以及1个郊区和1个农村社区中随机抽取的5686名受试者中的2100名进行了调查。该研究基于标准化问卷，并在必要时进行临床评估和实验室检查，由风湿科医生到目标人群家中进行。诊断采用既定的分类标准或为该研究设定的标准。
共有8740名受试者参与了研究（应答率82.1%）。在目标成年总人口中，经年龄和性别调整后的风湿性疾病总体患病率（患病率(asa)）为26.9%（95%可信区间26.2 - 27.6），女性（33.7%）显著高于男性（19.9%）（p < 0.0005）。疾病患病率(asa)随年龄显著增加（p < 0.0005）。最常见的疾病组是腰痛，患病率(asa)为11.0%，其次是有症状的外周骨关节炎（7.9%）、颈部疼痛（4.8%）、其他风湿性疾病（4.4%）、软组织风湿性疾病（4.3%）和炎性风湿性疾病（2.1%）。逻辑回归分析显示，女性或男性、年龄≥50岁、高体重指数、低教育水平、中度或重度饮酒以及高社会经济水平与特定疾病或疾病组之间存在显著的正相关。
这些发现表明风湿性疾病在希腊成年普通人群中非常常见；26.9%的成年人目前患有活动性或慢性缓解期风湿性疾病。
