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[溪黄草免疫功能的研究]

[Studies on immune function of Rabdosia excisa].

作者信息

Ye Lica, Chen Yanyan, Zhang Yang, Yang Huifen

机构信息

PLA 202 Hospital, Shenyang 110003.

出版信息

Zhong Yao Cai. 2003 Jan;26(1):33-5.

Abstract

OBJECTIVE

To study the immune function of Rabdosia excisa decoction.

METHODS

Weighting immune organ of mice, and studying the effects on carbon clearance rate in mice, lymphocyte transformation in vitro, the formation of serum hemolysin in mice and delayed hypersensitivity.

RESULTS

10 or 20 g/kg Rabdosia excisa decoction (RED) had no effect on spleen weight and thymus gland weight by ig. By i.p. 0.5, 2 g/kg RED or ig 20 g/kg RED, Rabdosia excisa group could inhibit the carbon clearance rate and lymphocyte transformation, but the group had no obvious effect on the formation of serum hemolysin. 2, 1, 0.5 and 0.25 g/kg RED could significantly inhibit delayed hypersensitivity by i.p.

CONCLUSION

RED could significantly inhibit reticuloendothelial system and cellular immunity, but had no obvious effect on humoral immunity.

摘要

目的

研究溪黄草水煎液的免疫功能。

方法

称量小鼠免疫器官重量,研究其对小鼠碳廓清率、体外淋巴细胞转化、小鼠血清溶血素形成及迟发型超敏反应的影响。

结果

灌胃给予10或20 g/kg溪黄草水煎液对小鼠脾脏重量和胸腺重量无影响。腹腔注射0.5、2 g/kg溪黄草水煎液或灌胃20 g/kg溪黄草水煎液,溪黄草组可抑制碳廓清率和淋巴细胞转化,但对血清溶血素形成无明显影响。腹腔注射2、1、0.5和0.25 g/kg溪黄草水煎液可显著抑制迟发型超敏反应。

结论

溪黄草水煎液可显著抑制网状内皮系统和细胞免疫,但对体液免疫无明显影响。

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