[Effect of Smilax china on adjunctive arthritis mouse].

OBJECTIVE

To study the therapeutic action of decoction of Smilax china L. on adjunctive arthritis(AA) mouse and its mechanism.

METHODS

To observe the change of secondary inflammation, thymus and spleen weights, T cell subgroup, B cell, NK cell.

RESULTS

The decoction (90, 180 g.kg-1) intragastric injection (ig) could significantly inhibit AA mouse's secondary inflammatory swelling, reduce thymus and spleen weights, decrease CD4/CD8, but had little influence on B Cell.

CONCLUSIONS

The decoction has therapeutic action by regulating cell-mediated immunity, but has little effect on humoral immunity.