Chan Louis Y, So William W, Lao Terence T
Department of Obstetrics and Gynaecology, Princess Margaret Hospital, Hong Kong, China.
Eur J Obstet Gynecol Reprod Biol. 2003 Aug 15;109(2):196-8. doi: 10.1016/s0301-2115(03)00011-3.
Ultrasound-guided aspiration is a less invasive management option for recurrent endometrioma. We postulated that the endometriotic tissue in the epithelial lining of endometrioma had undergone pressure atrophy after a period of observation, and resolution of the endometrioma can be achieved by aspiration of its content.
A prospective study was carried out in which patients with recurrent endometrioma that remain stationary in size for a period of at least 6 months were included. Ultrasound-guided aspiration of endometrioma was performed transvaginally under conscious sedation. Ultrasound scan examination was performed at 1, 3, 6, and 12 months after aspiration to detect recurrence.
Eight endometriomas were aspirated in six patients. The mean diameter and volume of endometrioma at aspiration were 31.0 mm (range, 18.0-46.3 mm) and 21.9 ml (range, 3.16-52.0 ml), respectively. There were no major complications. Cytological examination revealed hemosiderin-laden macrophages; neither malignant cells nor endometrial cells were detected in all cases. Six ovarian cysts recurred in five women (83.3%), all recurrence were detected within 3 months after aspiration.
We concluded that although transvaginal ultrasound-guided aspiration is a safe procedure, but the recurrence rate after aspiration is unacceptably high, and hence cannot be recommended as a treatment option for recurrent endometrioma.
超声引导下抽吸术是复发性卵巢子宫内膜异位囊肿一种侵入性较小的治疗选择。我们推测,卵巢子宫内膜异位囊肿上皮衬里中的异位内膜组织经过一段时间观察后会发生压力性萎缩,通过抽吸囊肿内容物可实现囊肿消退。
开展一项前瞻性研究,纳入囊肿大小稳定至少6个月的复发性卵巢子宫内膜异位囊肿患者。在清醒镇静下经阴道对卵巢子宫内膜异位囊肿进行超声引导下抽吸术。抽吸术后1、3、6和12个月进行超声扫描检查以检测复发情况。
6例患者的8个卵巢子宫内膜异位囊肿接受了抽吸术。抽吸时囊肿的平均直径和体积分别为31.0毫米(范围18.0 - 46.3毫米)和21.9毫升(范围3.16 - 52.0毫升)。未发生重大并发症。细胞学检查发现含铁血黄素巨噬细胞;所有病例均未检测到恶性细胞和子宫内膜细胞。5名女性(83.3%)出现6个卵巢囊肿复发,所有复发均在抽吸术后3个月内检测到。
我们得出结论,虽然经阴道超声引导下抽吸术是一种安全的操作,但抽吸术后复发率高得令人难以接受,因此不能推荐将其作为复发性卵巢子宫内膜异位囊肿的一种治疗选择。