恙虫病：清莱纤恙螨的媒介能力、恙虫病东方体的传播效力及分离

Scrub typhus: vector competence of Leptotrombidium chiangraiensis chiggers and transmission efficacy and isolation of Orientia tsutsugamushi.

作者信息

Lerdthusnee K, Khuntirat B, Leepitakrat W, Tanskul P, Monkanna T, Khlaimanee N, Inlao I, Kengluecha A, Mungviriya S, Chandranoi K, Krairojananan P, Bodhidatta D, Rodkwamthook W, Phulsuksombati D, Sangjun N, Watcharapichat P, Jones J W, Coleman R E

机构信息

Department of Entomology, Royal Thai Army Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.

出版信息

Ann N Y Acad Sci. 2003 Jun;990:25-35. doi: 10.1111/j.1749-6632.2003.tb07333.x.

DOI:10.1111/j.1749-6632.2003.tb07333.x

PMID:12860596

Abstract

A total of 4,281 rodents, belonging to 20 species, was collected from three villages in Chiangrai Province, northern Thailand, from January 1994 to December 2001. The predominant species were Rattus rattus, R. losea and Bandicota indica, accounting for 96% of the total. More than 135,000 chigger mites were removed from wild rodents of which 1% were identified as Leptotrombidium chiangraiensis, a new species vector of scrub typhus. Five Orientia tsutsugamushi-infected L. chiangraiensis colonies established from chiggers removed from R. rattus and R. losea rodents. The prevalence of O. tsutsugamushi infection in colonies ranged from 7-89%. Vertical and horizontal transmission efficacies of O. tsutsugamushi were stable between generations among colonies of L. chiangraiensis. The two isolates of O. tsutsugamushi obtained from individual adult L. chiangraiensis mites represent the first successful isolation of this bacterium from individual adult mites. Characterization of the O. tsutsugamushi isolates is under way.

摘要

1994年1月至2001年12月期间，从泰国北部清莱府的三个村庄收集了共计4281只啮齿动物，分属于20个物种。优势物种为黑家鼠、黄毛鼠和板齿鼠，占总数的96%。从野生啮齿动物身上采集到135000多只恙螨，其中1%被鉴定为清莱纤恙螨，这是恙虫病的一种新的传播媒介。从黑家鼠和黄毛鼠身上采集的恙螨建立了5个感染恙虫病东方体的清莱纤恙螨群落。恙虫病东方体在群落中的感染率为7%-89%。恙虫病东方体在清莱纤恙螨群落各代之间的垂直和水平传播效率稳定。从成年清莱纤恙螨个体中获得的两株恙虫病东方体分离株代表了首次成功从成年恙螨个体中分离出这种细菌。恙虫病东方体分离株的鉴定工作正在进行中。