D'Avanzo Barbara, La Vecchia Carlo, Negri Eva
Unità di Epidemiologia e Psichiatria Sociale, Istituto di Ricerche Farmacologiche Mario Negri, via Eritrea 62, 20157 Milan, Italy.
Soc Psychiatry Psychiatr Epidemiol. 2003 Jul;38(7):385-9. doi: 10.1007/s00127-003-0646-z.
Mortality in psychiatric patients both from natural and non-natural causes was reported to be markedly higher than in the general population. The effect of the psychiatric hospital (PH) closure process on mortality has nonetheless seldom been investigated. We studied mortality in a cohort of PH patients, taking into account the closure process in Italy.
A total of 2915 patients from 12 PH were described in the period 1994-1996 and followed up until June 2000, and discharges and deaths were registered. Standardized mortality ratios (SMR) for natural and non-natural causes were computed on the basis of regional death rates.
Observed deaths were 714 vs. 291.2 expected. The all-causes SMR was 2.47 in males and 2.43 in females. The SMR was 26.92 in males and 13.75 in females for psychiatric causes, 6.84 and 7.89 for undefined causes, 9.57 and 7.27 for pneumonia, 6.38 and 7.78 for chronic obstructive respiratory disease, and 1.27 and 1.58 for ischemic heart disease. No excess was observed for all cancers in males, but the SMR was 1.50 for lung cancer in males, 2.30 for breast cancer and 1.48 for all neoplasms in females. SMR for suicide was 3.85 in males and 2.73 in females. Most SMR were higher at younger age, although the rate of absolute excess deaths was greater above age 60. The SMR for all causes was 2.66 before discharge from PH, and 2.09 after discharge.
Mortality remained high after leaving the PH, but no increase was associated to the PH closure.
据报道,精神科患者因自然和非自然原因导致的死亡率明显高于普通人群。然而,精神病院(PH)关闭过程对死亡率的影响很少被研究。我们研究了一组PH患者的死亡率,并考虑了意大利的关闭过程。
1994年至1996年期间,对来自12家PH的2915名患者进行了描述,并随访至2000年6月,记录了出院和死亡情况。根据地区死亡率计算自然和非自然原因的标准化死亡率(SMR)。
观察到的死亡人数为714人,预期死亡人数为291.2人。男性全因SMR为2.47,女性为2.43。男性因精神疾病导致的SMR为26.92,女性为13.75;未明确原因的SMR为6.84和7.89;肺炎的SMR为9.57和7.27;慢性阻塞性呼吸道疾病的SMR为6.38和7.78;缺血性心脏病的SMR为1.27和1.58。男性所有癌症的SMR未观察到超标,但男性肺癌的SMR为1.50,女性乳腺癌的SMR为2.30,女性所有肿瘤的SMR为1.48。男性自杀的SMR为3.85,女性为2.73。大多数SMR在年轻时较高,尽管60岁以上的绝对超额死亡率更高。出院前所有原因的SMR为2.66,出院后为2.09。
离开PH后死亡率仍然很高,但与PH关闭无关。