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内罗毕肯雅塔国家医院因肿瘤导致的脊髓压迫症

Spinal cord compression due to tumours at Kenyatta National Hospital, Nairobi.

作者信息

Mwang'ombe N J, Ouma M B

机构信息

Department of Surgery, College of Health Sciences, University of Nairobi, P.O. Box 19676, Nairobi, Kenya.

出版信息

East Afr Med J. 2000 Jul;77(7):374-6. doi: 10.4314/eamj.v77i7.46680.

DOI:10.4314/eamj.v77i7.46680
PMID:12862156
Abstract

OBJECTIVE

To determine the frequency of different types of tumours associated with cord compression, their mode of presentation and treatment outcome.

DESIGN

Retrospective study.

SETTING

Kenyatta National Hospital (KNH), a teaching and referral hospital in Nairobi, Kenya, from January 1985 to December 1994.

SUBJECTS

Thirty eight patients.

RESULTS

There were twenty one males and seventeen females with a male/female ratio of 1.3:1 and a mean age of 36.9 years. Primary spinal cord tumours were more common (65.8%) than metastatic tumours (34.2%). The commonest spinal cord tumour was meningioma (23.7%) followed by neurofibroma (15.8%). Most of the patients (70%) did not show any clinical improvement after surgery.

CONCLUSION

Spinal cord tumours accounted for about 15% of all CNS tumours treated at the Kenyatta National Hospital. Most of the patients had total paralysis of the limbs at the time of presentation. Meningiomas and neurofibromas were the commonest cause of cord compression at KNH. Greater effort is needed to detect these tumours early when the signs and symptoms may be reversible following surgery.

摘要

目的

确定与脊髓压迫相关的不同类型肿瘤的发生率、其表现方式及治疗结果。

设计

回顾性研究。

地点

肯尼亚内罗毕的肯雅塔国家医院(KNH),一家教学及转诊医院,时间跨度为1985年1月至1994年12月。

研究对象

38名患者。

结果

男性21名,女性17名,男女比例为1.3:1,平均年龄36.9岁。原发性脊髓肿瘤比转移性肿瘤更常见(65.8%对34.2%)。最常见的脊髓肿瘤是脑膜瘤(23.7%),其次是神经纤维瘤(15.8%)。大多数患者(70%)术后未显示任何临床改善。

结论

脊髓肿瘤约占肯雅塔国家医院治疗的所有中枢神经系统肿瘤的15%。大多数患者就诊时四肢完全瘫痪。脑膜瘤和神经纤维瘤是肯雅塔国家医院脊髓压迫最常见的原因。需要做出更大努力以便在症状和体征在手术后可能可逆时早期发现这些肿瘤。

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