Eggeling T, Osterhues H H, Hoeher M, Gabrielsen F G, Weismueller P, Hombach V
Department of Cardiology-Angiology-Pneumology-Nephrology, University of Ulm, FRG.
Cardiology. 1992;81(2-3):107-14. doi: 10.1159/000175784.
The idiopathic long QT syndrome (LQTS) is an infrequently occurring disorder. It has major clinical impact as patients are prone to syncope, ventricular tachyarrhythmias and sudden arrhythmogenic cardiac death. This paper reports the value of ambulatory electrocardiogram (ECG) monitoring as a diagnostic tool to establish the diagnosis of LQTS. 14 patient with idiopathic LQTS were studied. The results were compared to those of 14 age- and sex-matched healthy control individuals. A 24-hour ambulatory ECG tracing was obtained in each individual. 5/14 patients with LQTS had pathological findings during ambulatory ECG monitoring (2 patients with episodes of torsade de pointes tachycardia, 2 patients with T-wave alternans and 1 patient with bradycardia due to an intermittent SA block), whereas all control persons had normal ambulatory ECG recordings (p < 0.03). Thus, ambulatory ECG recordings may contribute significant diagnostic information in patients with suspected LQTS.
特发性长QT综合征（LQTS）是一种罕见的疾病。它具有重大的临床影响，因为患者容易出现晕厥、室性快速心律失常和心律失常性心脏性猝死。本文报告了动态心电图（ECG）监测作为诊断LQTS的诊断工具的价值。研究了14例特发性LQTS患者。将结果与14名年龄和性别匹配的健康对照个体的结果进行比较。每个个体均进行了24小时动态心电图记录。14例LQTS患者中有5例在动态心电图监测期间有病理发现（2例有尖端扭转型室性心动过速发作，2例有T波交替，1例因间歇性窦房阻滞出现心动过缓），而所有对照者的动态心电图记录均正常（p<0.03）。因此，动态心电图记录可能为疑似LQTS患者提供重要的诊断信息。
