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异波帕明作为心脏移植前过渡治疗中多巴胺的一种有价值的辅助药物和替代药物。

Ibopamine as a valuable adjunct and substitute for dopamine in bridging therapy before heart transplantation.

作者信息

Kleber F X, Sabin G V, Thyroff-Friesinger U, Cabell B, Glogar D

机构信息

Krankenhaus München-Schwabing, Akademisches Lehrkrankenhaus der Ludwig-Maximilians-Universität, München, FRG.

出版信息

Cardiology. 1992;81(2-3):121-4. doi: 10.1159/000175786.

DOI:10.1159/000175786
PMID:1286470
Abstract

Ibopamine is an active dopamine analogue leading to improved renal perfusion and afterload reduction in heart failure. This report describes casuistic experiences in patients with severe heart failure awaiting heart transplantation. All patients could be stabilized, intravenous catecholamines be discontinued, and diuretics be reduced. Six of seven patients could be successfully transplanted. No major side effects were noted. Thus ibopamine can be a suitable adjunct for patients with endstage heart failure.

摘要

异波帕明是一种活性多巴胺类似物,可改善心力衰竭患者的肾灌注并降低后负荷。本报告描述了等待心脏移植的严重心力衰竭患者的个案经验。所有患者病情均可稳定,可停用静脉注射儿茶酚胺,并减少利尿剂用量。7例患者中有6例成功接受了移植。未观察到重大副作用。因此,异波帕明可以作为终末期心力衰竭患者的一种合适辅助药物。

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Ibopamine as a valuable adjunct and substitute for dopamine in bridging therapy before heart transplantation.异波帕明作为心脏移植前过渡治疗中多巴胺的一种有价值的辅助药物和替代药物。
Cardiology. 1992;81(2-3):121-4. doi: 10.1159/000175786.
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[Ibopamine--clinical results].[异波帕明——临床结果]
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The long-term efficacy of ibopamine in treating patients with severe heart failure: a multicenter investigation.异波帕胺治疗重度心力衰竭患者的长期疗效:一项多中心研究。
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Monitored long-term treatment with ibopamine in patients suffering from severe congestive heart failure.
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Ibopamine: long-term safety study in patients with congestive heart failure. The Italian Ibopamine Working Group.异波帕胺:充血性心力衰竭患者的长期安全性研究。意大利异波帕胺工作组
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引用本文的文献

1
Ibopamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in congestive heart failure.异波帕明。对其药效学和药代动力学特性以及在充血性心力衰竭中的治疗应用的综述。
Drugs Aging. 1993 Nov-Dec;3(6):556-84. doi: 10.2165/00002512-199303060-00008.