Marzeta Małgorzata, Toczołowski Jerzy
II Kliniki Okulistyki Akademii Medycznej w Lublinie.
Klin Oczna. 2003;105(1-2):60-2.
The aim of this study was to investigate the tears film, particularly mucin layer in patients with pterygium.
We examined 31 patients with pterygium--14 women and 17 men. Pterygium in one eye was found in 19 patients, in both eyes in 12. The control group consisted of 43 persons--21 women and 22 men. In our study were evaluated: marginal tears film, tears film break-up time (BUT), Schirmer's test and mucus fern patterns.
The results showed no statistically significant difference in Schirmer's test in both groups. Marginal tears film was incorrect in 65.12% of the eyes with pterygium and in 34.89% eyes of the control group. Tears film break-up time was reduced statistically significant, in patients with pterygium. Abnormal mucus fern patterns (type III and IV) was observed in 38.95% of the eyes with pterygium and in 13.94% of the eyes in the control group.
Disturbances of the tear film stability were found in the eyes with pterygium. The results of BUT and mucus fern patterns showed, that abnormalities of mucin layer to be responsible for these changes. Perhaps these observations will contribute to prevention of pterygium.
本研究旨在调查翼状胬肉患者的泪膜，尤其是黏蛋白层。
我们检查了31例翼状胬肉患者，其中14例女性，17例男性。19例患者一只眼睛患有翼状胬肉，12例患者双眼患有翼状胬肉。对照组由43人组成，其中21例女性，22例男性。在我们的研究中评估了：周边泪膜、泪膜破裂时间（BUT）、泪液分泌试验和黏液蕨类形态。
结果显示两组在泪液分泌试验中无统计学显著差异。65.12%的翼状胬肉患眼和34.89%的对照组患眼周边泪膜异常。翼状胬肉患者的泪膜破裂时间在统计学上显著缩短。38.95%的翼状胬肉患眼和13.94%的对照组患眼观察到异常的黏液蕨类形态（III型和IV型）。
在翼状胬肉患眼中发现泪膜稳定性受到干扰。泪膜破裂时间和黏液蕨类形态的结果表明，黏蛋白层异常是这些变化的原因。也许这些观察结果将有助于翼状胬肉的预防。
