Avkhodiev G I, Kuz'mina O V
Sud Med Ekspert. 2003 Mar-Apr;46(2):13-6.
Postmortem examinations of cytomedines of internal organs in 181 men showed a possibility to use their (cytomedines') quantitative and qualitative characteristics as diagnostic criteria of stress influencing the human organism shortly before the death onset. Bioregulatory peptides were obtained by using Morozov's and Khavinson's method of acetous extraction. The composition of cytomedines was determined by spectrophotometer, while their biological activity (BA) was studied through affecting the phagocytic activity of blood neutrophils. It was concluded that, under stress, there are a significant inhibition of BA and a reduced count of cytomedines in the internal organs. The found data can be used to detect the stress preceding death.
对181名男性的内脏细胞调节因子进行尸检发现,有可能利用其(细胞调节因子的)定量和定性特征作为死亡发作前不久影响人体的应激诊断标准。采用莫罗佐夫和哈维森的醋酸提取法获得生物调节肽。用分光光度计测定细胞调节因子的组成,同时通过影响血液中性粒细胞的吞噬活性来研究其生物活性(BA)。得出的结论是,在应激状态下,生物活性受到显著抑制,内脏器官中的细胞调节因子数量减少。所发现的数据可用于检测死前的应激状态。