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[甲状腺功能减退对犬心脏功能的影响]

[The effect of hypothyroidism on cardiac function in dogs].

作者信息

Stephan I, Nolte I, Hoppen H O

机构信息

Klinik für kleine Haustiere der Tierärztlichen Hochschule Hannover, Zentrumsabteilung für chemische Analytik und Endokrinologie der Tierärztlichen Hochschule Hannover.

出版信息

Dtsch Tierarztl Wochenschr. 2003 Jun;110(6):231-9.

Abstract

The thyroid hormones have direct and indirect effects on the heart. So it is possible that depression of left ventricular function is associated with hypothyroidism. This publication describes cardiac findings (auscultation, electrocardiography, echocardiography) in ten hypothyroid dogs. Low heart rates, reduced R-amplitudes and bradycardic arrhythmias (first and second-degree AV block) were found on the electrocardiogram before treatment. On the echocardiograms most of the dogs showed reduced contractillity and reduced left ventricular wall thickness. Seven dogs were reexamined after levothyroxine supplementation. Effects of treatment were increased heart rates and R-amplitudes as well as disappearance of the bradycardic arrhythmias in electrocardiographic examination. The echocardiographic examination showed increased contractility and increased left ventricular wall thickness.

摘要

甲状腺激素对心脏有直接和间接影响。因此,左心室功能减退可能与甲状腺功能减退有关。本出版物描述了十只甲状腺功能减退犬的心脏检查结果(听诊、心电图、超声心动图)。治疗前心电图显示心率降低、R波振幅降低和缓慢性心律失常(一度和二度房室传导阻滞)。超声心动图显示,大多数犬的心肌收缩力降低,左心室壁厚度减小。七只犬在补充左甲状腺素后接受复查。治疗效果表现为心率和R波振幅增加,心电图检查中缓慢性心律失常消失。超声心动图检查显示心肌收缩力增强,左心室壁厚度增加。

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