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[扫描电子显微镜下鼻息肉的表面]

[The surface of nasal polyps in the scanning electron microscope].

作者信息

Lenz H

出版信息

Laryngol Rhinol Otol (Stuttg). 1975 Dec;54(12):950-64.

PMID:128674
Abstract

23 specimens with endonasal polyposis are examined scanning-electron-microscopically. There is a domination of kinocilia-free epithelium. The latter is bulging out in a dome-shaped manner, extensively loosened, showing transitional forms from cylindrical epithelium to more cube-like and finally squamous epithelium. The cylindrical epithelium is partly closely joined, showing ballon-like bulgings, cytoplasmatic protuberances, filled beaker cells with reduced or missing microvilly and partially granulating surface as well as emptying beaker cells with a thin microvilly edge. The covered surface shows partially normal lawn- and/or bundle-like, long and most parallel kinociliae, and short thin kinociliae in small bundles. All of them have a coordinated direction and a morphologically evident function-phase. In addition there is a network of kinociliae without function-phase and coordinated direction, which may or may not be covered by mucous, as well as damage and reproliferation of kinociliae. By reason of the morphological findings one can come to the conclusion that there is an extensive decrease in function of the mucociliar system in case of polyposis and as a consequence of this bacterial and viral infections might be favoured.

摘要

对23例鼻内息肉标本进行扫描电子显微镜检查。无动纤毛上皮占主导地位。后者呈圆顶状突出,广泛疏松,呈现从柱状上皮到更立方状、最终鳞状上皮的过渡形式。柱状上皮部分紧密相连,呈现气球样隆起、细胞质突起,杯状细胞内微绒毛减少或缺失且表面部分颗粒化,以及微绒毛边缘薄的排空杯状细胞。覆盖表面部分显示正常的草坪状和/或束状、长且大多平行的动纤毛,以及小束状的短细动纤毛。所有这些动纤毛都有协调的方向和形态学上明显的功能阶段。此外,还有一个无功能阶段和协调方向的动纤毛网络,其可能被黏液覆盖也可能未被覆盖,以及动纤毛的损伤和再增殖。根据形态学发现可以得出结论,息肉病时黏液纤毛系统功能广泛降低,因此可能有利于细菌和病毒感染。

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