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采用下颌骨内部牵张成骨术矫正新生儿上气道梗阻。

Correction of upper airway obstruction in the newborn with internal mandibular distraction osteogenesis.

作者信息

Izadi Keyoumars, Yellon Robert, Mandell David L, Smith Meghan, Song Sung Y, Bidic Sean, Bradley James P

机构信息

Children's Hospital of Pittsburgh, Division of Plastic and Reconstructive Surgery, University of Pittsburgh, Pennsylvania, USA.

出版信息

J Craniofac Surg. 2003 Jul;14(4):493-9. doi: 10.1097/00001665-200307000-00019.

Abstract

Tracheostomy for management of neonatal airway obstruction may be life saving but is associated with complications and developmental problems. As an alternative, the effectiveness of internal mandibular distraction osteogenesis was investigated in select neonatal patients with micrognathia and upper airway obstruction. Preoperative tests (sleep study, direct laryngobronchoscopy, and "milk scan" for GI reflux) were used to select appropriate candidates for the procedure. Excluded were patients with 1) central apnea, 2) severe reflux, 3) other airway lesions, and 4) mild to moderate obstruction controlled by positioning. Of 44 newborns (aged <3 weeks) with upper airway obstruction and micrognathia seen in the neonatal intensive care unit, 19 underwent tracheostomy, 10 were discharged with home monitoring and positional instructions, and 15 underwent bilateral mandibular lengthening with microdistractors. Of those who underwent mandibular distraction, a tracheostomy was avoided in 14 of 15 patients. Relative improvement in the posterior airway space was seen on 3D CT scans, cephalograms, and laryngobronchoscopies obtained preoperatively, postoperatively, and during follow-up evaluation. One of these 15 patients required a tracheostomy for postoperative central apnea. In an average of just 4.5 days following completion of distraction, patients were discharged home with improved oral feeding and no feeding tube. This study suggests that for selected newborns, the use of internal microdistractors allows for avoidance of a tracheostomy and improved oral feeding.

摘要

气管切开术用于治疗新生儿气道阻塞可能挽救生命,但会伴有并发症和发育问题。作为一种替代方法,对部分患有小颌畸形和上气道阻塞的新生儿患者,研究了下颌骨内牵张成骨术的有效性。术前检查(睡眠研究、直接喉镜检查和用于胃食管反流的“奶液扫描”)用于筛选适合该手术的患者。排除标准为:1)中枢性呼吸暂停;2)严重反流;3)其他气道病变;4)通过体位可控制的轻至中度阻塞。在新生儿重症监护病房就诊的44例患有上气道阻塞和小颌畸形的新生儿(年龄<3周)中,19例行气管切开术,10例在接受家庭监测和体位指导后出院,15例行双侧下颌骨微型牵张延长术。在接受下颌骨牵张的患者中,15例中有14例避免了气管切开术。在术前、术后及随访评估时获取的三维CT扫描、头颅侧位片和喉镜检查中,可见气道后间隙相对改善。这15例患者中有1例因术后中枢性呼吸暂停需要行气管切开术。平均在牵张完成后仅4.5天,患者即可出院回家,经口喂养改善且无需鼻饲管。本研究表明,对于部分新生儿,使用微型牵张器可避免气管切开术并改善经口喂养。

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