Elkington Nicholas M, Kehoe Jane, Acharya Umesh
Centre for Reproductive Medicine, Derriford Hospital, Plymouth PL6 8DH, UK.
Hum Fertil (Camb). 2003 May;6(2):74-6. doi: 10.1080/1464770312331369083.
A postal questionnaire was sent to all assisted conception units (ACUs) in the UK that undertake IVF. The return rate was 62 of 74 (84%). The majority of units (84%) used intravenous (i.v.) sedation for transvaginal egg collection, whereas 16% used general anaesthesia. There was a great deal of variation in personnel present during the procedure, the use of drugs, the degree of monitoring and the availability of emergency drugs. Most units titrate an i.v. benzodiazepine and i.v. opiate manually, usually midazolam and fentanyl, respectively. This audit demonstrates the wide variation in current UK practice and highlights the need for the adoption of national guidelines for safe use of i.v. sedation in ACUs.
一份邮政调查问卷被寄给了英国所有开展体外受精的辅助生殖单位(ACU)。回复率为74个单位中的62个(84%)。大多数单位(84%)在经阴道取卵时使用静脉镇静,而16%使用全身麻醉。在操作过程中在场的人员、药物的使用、监测程度以及急救药物的可用性方面存在很大差异。大多数单位手动滴定静脉注射苯二氮䓬类药物和静脉注射阿片类药物,通常分别为咪达唑仑和芬太尼。本次审核表明了英国目前做法的广泛差异,并强调了在辅助生殖单位采用静脉镇静安全使用国家指南的必要性。