Maier D B, Nulsen J C, Klock A, Luciano A A
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington 06030.
J Reprod Med. 1992 Dec;37(12):965-8.
Severe adhesions were induced at laparotomy by laser ablation of the surface of one uterine horn and 1 cm2 of pelvic sidewall in 20 rabbits. Three weeks later the rabbits were selected at random for laparoscopy or laparotomy. Adhesions at the horn, sidewall and incidental sites were scored and lysed with laser at similar power densities. Three weeks later animals were killed and adhesions were blindly scored. We found a significant and similar reduction in severe adhesions at uterine horns after either laser laparoscopy or laser laparotomy, better lysis of sidewall and incidental adhesions by laser laparoscopy and formation of de novo adhesions at nonoperative sites after laparotomy but not after laparoscopy. We conclude that (1) de novo adhesions are common after laparotomy; (2) severe uterine horn adhesions can be reduced equally well by both laparoscopy and laparotomy but laparoscopy is superior to laparotomy with less severe peripheral adhesions; (3) outcome of adhesiolysis depends on several variables, including adhesion density and location and approach (laparotomy or laparoscopy), even when the tool (laser) is constant.
通过激光烧灼20只兔子一侧子宫角表面和1平方厘米盆腔侧壁,在剖腹手术时诱导产生严重粘连。三周后,随机选择兔子进行腹腔镜检查或剖腹手术。对子宫角、侧壁和偶然部位的粘连进行评分,并用相似功率密度的激光进行松解。三周后处死动物,对粘连进行盲法评分。我们发现,激光腹腔镜检查或激光剖腹手术后,子宫角严重粘连均有显著且相似程度的减轻,激光腹腔镜检查对侧壁和偶然粘连的松解效果更好,剖腹手术后非手术部位出现了新粘连形成,而腹腔镜检查后未出现。我们得出结论:(1)剖腹手术后新粘连形成很常见;(2)腹腔镜检查和剖腹手术对减轻严重子宫角粘连的效果相当,但腹腔镜检查在减轻外周较轻粘连方面优于剖腹手术;(3)粘连松解的结果取决于多个变量,包括粘连密度、位置和手术方式(剖腹手术或腹腔镜检查),即使工具(激光)不变。