Vangronsveld Erik, Mandel Friedrich
Huntsman Polyurethanes, Everslaan 45, 3078 Everberg, Belgium.
Rapid Commun Mass Spectrom. 2003;17(15):1685-90. doi: 10.1002/rcm.1106.
A sensitive liquid chromatography/ion trap tandem mass spectrometry method was developed for the qualitative and quantitative detection of isocyanates in air. The method is based on derivatization of isocyanates with 1-(2-methoxyphenyl)piperazine during air sampling. The extracts are analyzed using an ion trap LC/MS system equipped with an electrospray (ESI) ion source. The method shows high linearity, specificity, accuracy and precision. The limits of detection are 40x to 55x lower than with UV-based methods.
开发了一种灵敏的液相色谱/离子阱串联质谱法，用于空气中异氰酸酯的定性和定量检测。该方法基于在空气采样过程中用1-(2-甲氧基苯基)哌嗪对异氰酸酯进行衍生化。提取物使用配备电喷雾（ESI）离子源的离子阱液相色谱/质谱系统进行分析。该方法具有高线性、特异性、准确性和精密度。检测限比基于紫外的方法低40倍至55倍。
