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[肠易激综合征——标准、亚分类、病因]

[Irritable bowel syndrome--criteria, sub-classification, etiology].

作者信息

Okamura S, Sekiguchi T

机构信息

Gunma University, 1st Department of Internal Medicine.

出版信息

Nihon Rinsho. 1992 Nov;50(11):2686-90.

PMID:1287243
Abstract

The irritable bowel syndrome (IBS) is a very common condition in gastroenterology clinics, but yet it is one of the pooly understood. A international working team in Rome, 1988, proposed that IBS is a functional intestinal disorder with chronic or recurrent gastrointestinal symptoms without structural or biochemical abnormalities. IBS was sub-classified into 3 groups; abdominal pain as the prominent feature with diarrhea, with constipation, with both while painless diarrhea and simple constipation without pain were excluded from IBS. There is a lot of data suggesting that IBS has a gut dysmotility, which is influenced by many stimuli (food, hormone, drug, menses, mechanical dilatation), including psychological stress. Moreover, currently available evidences implicate that IBS is a more generalized disorder of smooth muscle function not only in the intestine but also outside of the intestine.

摘要

肠易激综合征(IBS)在胃肠病诊所中是一种非常常见的病症,但它也是最不为人所了解的病症之一。1988年,罗马的一个国际工作团队提出,IBS是一种功能性肠道疾病,伴有慢性或复发性胃肠道症状,但无结构或生化异常。IBS被分为3组;以腹痛为突出特征,伴有腹泻、便秘,或两者皆有,而无痛性腹泻和单纯便秘则被排除在IBS之外。有大量数据表明,IBS存在肠道动力障碍,这受到许多刺激因素(食物、激素、药物、月经、机械扩张)的影响,包括心理压力。此外,目前可得的证据表明,IBS不仅是肠道平滑肌功能的一种更广泛的紊乱,也是肠道外平滑肌功能的紊乱。

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