Nakahara A, Kashimura H, Fukutomi H
Department of Medicine, University of Tsukuba.
Nihon Rinsho. 1992 Nov;50(11):2712-8.
The exact etiology of irritable bowel syndrome (IBS) is unknown. IBS is probably one of the commonest gastrointestinal disorders, but it has proved to be one of the most difficult conditions to diagnose. A proportion of patients give a strong history of stress-related or stress-evoked symptoms. In the past there has been a paucity of studies of this disorder because of difficulties in patient selection, choice of appropriate marker to be tested and the correlation of findings with the clinical presentation. A clear and precise definition of IBS is of most importance in the understanding of psychopathophysiological markers in this disorders.
肠易激综合征（IBS）的确切病因尚不清楚。IBS可能是最常见的胃肠道疾病之一，但事实证明它也是最难诊断的疾病之一。一部分患者有与压力相关或压力诱发症状的强烈病史。过去，由于患者选择困难、难以选择合适的检测标志物以及研究结果与临床表现的相关性等问题，对这种疾病的研究较少。明确而精确地定义IBS对于理解该疾病的心理病理生理学标志物至关重要。
