Strangway A, Fowler R, Cunningham K, Hamilton J R
Pediatrics. 1976 Jan;57(1):75-86.
To assess the relationship between diet and growth in congenital heart disease we studied nutrient intake, body measurements, and cardiac status in 568 affected ambulatory patients less than 11 years of age. Most had mild heart disease, 104 were cyanotic, and only 10 were in congestive heart failure. Major disturbances of growth were uncommon. For the entire group body weight was below normal but only in those studied before 2 years of age; rate of growth and weight gain were normal over the period preceding the dietary study. There was no statistically significant relationship between intake of calories, protein, or other nutrients and growth or gain, analyzing the entire group, or analyzing patients subgrouped according to age, severity of heart disease, or severity of growth retardation. Body size and growth were diminished in cyanosed compared with noncyanosed children but cardiac status had no effect on nutrient intake. We conclude that in children with growth failure associated with congenital heart disease, nutrient intake is not an important factor limiting their growth.
为评估饮食与先天性心脏病患儿生长发育之间的关系，我们对568名年龄小于11岁的非卧床先天性心脏病患儿的营养摄入、身体测量指标及心脏状况进行了研究。多数患儿患有轻度心脏病，104名患儿有发绀症状，仅有10名患儿出现充血性心力衰竭。生长发育的严重障碍并不常见。对于整个研究群体，仅2岁前接受研究的患儿体重低于正常水平；在饮食研究前的一段时间内，生长速率和体重增加均正常。分析整个研究群体，或根据年龄、心脏病严重程度或生长发育迟缓严重程度对患儿进行分组分析，结果显示热量、蛋白质或其他营养素的摄入量与生长发育或体重增加之间均无统计学意义上的显著关联。与无发绀症状的儿童相比，发绀儿童的体型和生长发育受到影响，但心脏状况对营养摄入并无影响。我们得出结论，对于患有与先天性心脏病相关生长发育障碍的儿童，营养摄入并非限制其生长的重要因素。
