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为什么先天性心脏病会导致发育不良?

Why does congenital heart disease cause failure to thrive?

作者信息

Menon G, Poskitt E M

出版信息

Arch Dis Child. 1985 Dec;60(12):1134-9. doi: 10.1136/adc.60.12.1134.

DOI:10.1136/adc.60.12.1134
PMID:4091578
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1777687/
Abstract

Metabolisable energy intake, determined by bomb calorimetry of food, vomit, stool and urine, and resting metabolism, assessed by respiratory gas exchange, were studied in 21 infants with congenital heart disease and nine control infants. Weight for age, growth rates, and daily metabolisable energy intake per kg tended to be lower in infants with heart disease than in control infants. Resting oxygen consumption was high in those infants with pulmonary hypertension and persistent cardiac failure. Energy intake, as a percentage of that recommended for age, correlated with weight gain, and resting oxygen consumption correlated inversely with both percentage body mass index and relative fatness. Failure to thrive in infants with congenital heart disease may be due to a combination of low energy intakes and, in some cases, high energy requirements allowing insufficient energy for normal growth. Increasing the energy intakes of infants with congenital heart disease may be a way of improving their growth.

摘要

通过对食物、呕吐物、粪便和尿液进行弹式量热法测定可代谢能量摄入,并通过呼吸气体交换评估静息代谢,对21名先天性心脏病婴儿和9名对照婴儿进行了研究。患有心脏病的婴儿的年龄别体重、生长速率和每千克每日可代谢能量摄入往往低于对照婴儿。患有肺动脉高压和持续性心力衰竭的婴儿静息耗氧量较高。能量摄入量占推荐年龄摄入量的百分比与体重增加相关,静息耗氧量与体重指数百分比和相对肥胖程度呈负相关。先天性心脏病婴儿生长发育不良可能是由于能量摄入低,以及在某些情况下能量需求高,导致正常生长所需能量不足。增加先天性心脏病婴儿的能量摄入量可能是促进其生长的一种方法。

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