Møller D S, Dideriksen A, Sørensen S, Madsen L D, Pedersen E B
Department of Medicine, Holstebro Hospital and Aarhus University, Holstebro, Denmark.
J Hum Hypertens. 2003 Aug;17(8):549-54. doi: 10.1038/sj.jhh.1001584.
This study was conducted to compare the accuracy of clinic blood pressure (CBP) and telemedical home blood pressure (HBP) measurement in the diagnosis of hypertension in primary care. The study subjects were 411 patients with average CBP > or =140 mmHg systolic or > or =90 mmHg diastolic, who performed telemedical HBP measurement (5 days, four times daily) and ambulatory blood pressure (ABP) monitoring in random order. Main outcome measure was the agreement of CBP and HBP with daytime ABP. CBP was much higher than daytime ABP and average HBP (P<0.001) with no difference between the latter two. The correlation between CBP and ABP was weak (systolic: r=0.499, diastolic: r=0.543), whereas strong correlations existed between HBP and ABP (systolic: r=0.847, diastolic: r=0.812). A progressive improvement in the strength of the linear regression between average HBP of single days and ABP was obtained from day 1 to day 4, with no further benefit obtained on the fifth day. The HBP readings taken at noon and in the afternoon showed significantly stronger correlations with ABP than the blood pressures measured in the morning and in the evening. In conclusion, the accuracy of telemedical HBP measurement was substantially better than that of CBP in the diagnosis of hypertension in primary care. HBP most accurately reflected ABP on the fourth day of monitoring, and the readings at noon and in the afternoon seemed to be most accurate.
本研究旨在比较诊所血压(CBP)测量与远程医疗家庭血压(HBP)测量在基层医疗中诊断高血压的准确性。研究对象为411例患者,其平均收缩压CBP≥140 mmHg或舒张压≥90 mmHg,这些患者按随机顺序进行远程医疗HBP测量(5天,每天4次)及动态血压(ABP)监测。主要观察指标是CBP和HBP与日间ABP的一致性。CBP远高于日间ABP及平均HBP(P<0.001),而后两者之间无差异。CBP与ABP的相关性较弱(收缩压:r=0.499,舒张压:r=0.543),而HBP与ABP之间存在较强的相关性(收缩压:r=0.847,舒张压:r=0.812)。从第1天到第4天,单日平均HBP与ABP之间线性回归的强度逐步提高,第5天未获得进一步改善。中午和下午测量的HBP读数与ABP的相关性明显强于早晨和晚上测量的血压。总之,在基层医疗中诊断高血压时,远程医疗HBP测量的准确性明显优于CBP。在监测的第4天,HBP最准确地反映了ABP,中午和下午的读数似乎最准确。