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铅对红细胞膜的影响。

The effect of lead on the red cell membrane.

作者信息

Selhi H S, White J M

出版信息

Postgrad Med J. 1975 Nov;51(601):765-9. doi: 10.1136/pgmj.51.601.765.

Abstract

Conformational changes have been shown in the proteins of the red blood cell membrane, induced by lead poisoning. Evidence that the change in spatial arrangement of proteins is believed to be responsible for inhibition of the sodium (Na)/potassium (K) ATPase of the RBC membrane is presented.

摘要

铅中毒可导致红细胞膜蛋白发生构象变化。文中提供了证据表明,蛋白质空间排列的改变被认为是红细胞膜钠(Na)/钾(K)ATP酶受到抑制的原因。

相似文献

1
The effect of lead on the red cell membrane.铅对红细胞膜的影响。
Postgrad Med J. 1975 Nov;51(601):765-9. doi: 10.1136/pgmj.51.601.765.
2
Lead and the red cell.
Br J Haematol. 1975 Jun;30(2):133-8. doi: 10.1111/j.1365-2141.1975.tb00526.x.
3
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Lead and haemoglobin synthesis: a review.铅与血红蛋白合成:综述
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Ecotoxicol Environ Saf. 2009 Jan;72(1):37-44. doi: 10.1016/j.ecoenv.2008.05.004. Epub 2008 Jun 24.

引用本文的文献

本文引用的文献

4
Uptake of lead by human erythrocytes in vitro.人红细胞对铅的体外摄取。
Biochem J. 1958 Jul;69(3):432-9. doi: 10.1042/bj0690432.
5
Enhanced potassium loss in blood cells from men exposed to lead.接触铅的男性血细胞中钾流失增加。
Arch Environ Health. 1967 Feb;14(2):309-12. doi: 10.1080/00039896.1967.10664737.
6
Exposed protein on the intact human erythrocyte.完整人类红细胞上暴露的蛋白质。
Biochemistry. 1971 May 11;10(10):1766-71. doi: 10.1021/bi00786a006.
9
Red cell membrane ATPase in workers exposed to inorganic lead.
Arch Environ Health. 1967 Feb;14(2):319-24. doi: 10.1080/00039896.1967.10664739.
10
Deficient red cell membrane /Na++K+/-ATPase in lead poisoning.
Arch Environ Health. 1967 Feb;14(2):313-8. doi: 10.1080/00039896.1967.10664738.

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