一项关于长期接触钍尘影响的20年随访研究。
A 20-year follow-up study on the effects of long-term exposure to thorium dust.
作者信息
Chen Xing'an, Cheng Yonge, Xiao Huijuan, Feng Guodong, Deng Yunhui, Feng Zhiliang, Chen Lian, Han Xuanmao, Yang Yingjie, Dong Zhihuan, Zhen Rong
机构信息
Laboratory of Industrial Hygiene, Ministry of Health, Beijing 100088, China.
出版信息
Chin Med J (Engl). 2003 May;116(5):692-4.
OBJECTIVE
To investigate the possible effects of long-term exposure to dust containing thorium and thoron progeny on dust-exposed miners.
METHODS
A negative, high voltage, exhaled thoron progeny measurement system was used to estimate the miners' thorium lung burden.
RESULTS
The highest thorium lung burden of 638 miners was 11.11 Bq. The incidence of stage 0(+) pneumoconiosis was higher among dust-exposed miners. Lung cancer mortality of the dust-exposed miners was significantly higher than that of controls (P < 0.005).
CONCLUSION
There is a difference in cancer rates between those who have long-term exposure to dust containing thorium (in which carcinogenic ThO(2) and SiO(2) exist) and thoron progeny and those who have not.
目的
探讨长期接触含钍及钍射气子体粉尘对接触粉尘矿工的可能影响。
方法
采用负压、高压呼出钍射气子体测量系统估算矿工的钍肺负荷。
结果
638名矿工的最高钍肺负荷为11.11贝可。接触粉尘矿工的0（+）期尘肺病发病率较高。接触粉尘矿工的肺癌死亡率显著高于对照组（P < 0.005）。
结论
长期接触含钍（其中存在致癌性二氧化钍和二氧化硅）及钍射气子体粉尘者与未接触者之间的癌症发生率存在差异。
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