Pisoni Cecilia N, Grinberg Alejandro R, Plana José L, Freue Roberto D, Manni Jorge A, Paz Leonardo
Servicio de Inmunología, Instituto de Investigaciones Médicas Alfredo Lanari, Combatientes de Malvinas 3150, 1427 Buenos Aires, Argentina.
Medicina (B Aires). 2003;63(3):221-3.
A 36 year-old woman with systemic lupus erythematosus was admitted to our hospital with headache, brachiocrural hemiparesis and hemianesthesia. She had been treated with prednisone and cyclophosphamide. CT scan and MRI revealed a 15 mm nodular mass enhanced with gadolinium in left frontal convexity. CNS biopsy was performed and a diffuse large B-cell lymphoma was diagnosed. She was treated with radiation therapy without response and died. There are few reports of erythematosus systemic lupus associated with primary central nervous system lymphoma.
一名36岁的系统性红斑狼疮女性因头痛、臂腿部偏瘫和偏身感觉缺失入住我院。她曾接受泼尼松和环磷酰胺治疗。CT扫描和MRI显示左额凸面有一个15毫米的结节状肿块,钆增强。进行了中枢神经系统活检,诊断为弥漫性大B细胞淋巴瘤。她接受了放射治疗但无反应,最终死亡。关于系统性红斑狼疮与原发性中枢神经系统淋巴瘤相关的报道很少。